Assessment of immunostimulatory responses to the antimiR-22 oligonucleotide compound RES-010 in human peripheral blood mononuclear cells

microRNA-22 (miR-22) is a key regulator of lipid and energy homeostasis and represents a promising therapeutic target for NAFLD and obesity. We have previously identified a locked nucleic acid (LNA)-modified antisense oligonucleotide compound complementary to miR-22, designated as RES-010 that media...

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Detalles Bibliográficos
Autores principales: Panella, Riccardo, Zanderigo, Floriana, Morandini, Francesca, Federico, Denise, Vicentini, Elena, Andreetta, Filippo, Toniolo, Alessandro, Kauppinen, Sakari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076763/
https://www.ncbi.nlm.nih.gov/pubmed/37033600
http://dx.doi.org/10.3389/fphar.2023.1125654

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076763/
https://www.ncbi.nlm.nih.gov/pubmed/37033600
http://dx.doi.org/10.3389/fphar.2023.1125654

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