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Assessment of immunostimulatory responses to the antimiR-22 oligonucleotide compound RES-010 in human peripheral blood mononuclear cells
microRNA-22 (miR-22) is a key regulator of lipid and energy homeostasis and represents a promising therapeutic target for NAFLD and obesity. We have previously identified a locked nucleic acid (LNA)-modified antisense oligonucleotide compound complementary to miR-22, designated as RES-010 that media...
Autores principales: | Panella, Riccardo, Zanderigo, Floriana, Morandini, Francesca, Federico, Denise, Vicentini, Elena, Andreetta, Filippo, Toniolo, Alessandro, Kauppinen, Sakari |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076763/ https://www.ncbi.nlm.nih.gov/pubmed/37033600 http://dx.doi.org/10.3389/fphar.2023.1125654 |
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