Extranodal marginal zone lymphoma clonotypes are detectable prior to eMZL diagnosis in tissue biopsies and peripheral blood of Sjögren’s syndrome patients through immunogenetics

INTRODUCTION: Activated B cells play a key role in the pathogenesis of primary Sjögren’s syndrome (pSS) through the production of autoantibodies and the development of ectopic germinal centers in the salivary glands and other affected sites. Around 5-10% of pSS patients develop B-cell lymphoma, usua...

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Detalles Bibliográficos
Autores principales: Kolijn, P. Martijn, Huijser, Erika, Wahadat, M. Javad, van Helden-Meeuwsen, Cornelia G., van Daele, Paul L. A., Brkic, Zana, Rijntjes, Jos, Hebeda, Konnie M., Groenen, Patricia J. T. A., Versnel, Marjan A., Thurlings, Rogier M., Langerak, Anton W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076775/
https://www.ncbi.nlm.nih.gov/pubmed/37035202
http://dx.doi.org/10.3389/fonc.2023.1130686

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