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Zanubrutinib for the treatment of lymphoid malignancies: Current status and future directions

Zanubrutinib (BGB-3111, Brukinsa(®), BeiGene) is a next-generation irreversible inhibitor of Bruton’s tyrosine kinase (BTK), developed by BeiGene in 2012 for the treatment of B-cell malignancies. It was designed to minimize off-target inhibition of TEC- and EGFR-family kinases. Zanubrutinib is more...

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Detalles Bibliográficos
Autores principales: Wolska-Washer, Anna, Robak, Tadeusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076791/
https://www.ncbi.nlm.nih.gov/pubmed/37035197
http://dx.doi.org/10.3389/fonc.2023.1130595