Activation of ventral tegmental area vesicular GABA transporter (Vgat) neurons alleviates social defeat stress-induced anxiety in APP/PS1 mice

INTRODUCTION: Alzheimer’s disease (AD) is a progressive neurodegenerative disease that results in cognitive impairment and is often accompanied by anxiety. In this study, we investigated whether the activation of VTA(Vgat) neurons could reduce anxiety in APP/PS1 mice. We hypothesized that acute soci...

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Detalles Bibliográficos
Autores principales: Yao, Di, Li, Rong, Kora, Musa, Huang, Hongqing, Liu, Xinghua, Gong, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Aging Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076796/
https://www.ncbi.nlm.nih.gov/pubmed/37032820
http://dx.doi.org/10.3389/fnagi.2023.1142055

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