Randomized phase III study of high-dose methotrexate and whole-brain radiotherapy with/without temozolomide for newly diagnosed primary CNS lymphoma: JCOG1114C

BACKGROUND: The goal was to determine whether the addition of temozolomide (TMZ) to the standard treatment of high-dose methotrexate (HD-MTX) and whole-brain radiotherapy (WBRT) for primary central nervous system lymphoma (PCNSL) improves survival. METHODS: An open-label, randomized, phase III trial...

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Detalles Bibliográficos
Autores principales: Mishima, Kazuhiko, Nishikawa, Ryo, Narita, Yoshitaka, Mizusawa, Junki, Sumi, Minako, Koga, Tomoyuki, Sasaki, Nobuyoshi, Kinoshita, Manabu, Nagane, Motoo, Arakawa, Yoshiki, Yoshimoto, Koji, Shibahara, Ichiyo, Shinojima, Naoki, Asano, Kenichiro, Tsurubuchi, Takao, Sasaki, Hikaru, Asai, Akio, Sasayama, Takashi, Momii, Yasutomo, Sasaki, Atsushi, Nakamura, Shigeo, Kojima, Masaru, Tamaru, Jun-ichi, Tsuchiya, Kazuhiro, Gomyo, Miho, Abe, Kayoko, Natsumeda, Manabu, Yamasaki, Fumiyuki, Katayama, Hiroshi, Fukuda, Haruhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Clinical Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076938/
https://www.ncbi.nlm.nih.gov/pubmed/36334050
http://dx.doi.org/10.1093/neuonc/noac246

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