A distinct pattern of growth and RAC1 signaling in melanoma brain metastasis cells

BACKGROUND: Melanoma, the deadliest of skin cancers, has a high propensity to form brain metastases that are associated with a markedly worsened prognosis. In spite of recent therapeutic advances, melanoma brain lesions remain a clinical challenge, biomarkers predicting brain dissemination are not c...

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Detalles Bibliográficos
Autores principales: Stejerean-Todoran, Ioana, Gimotty, Phyllis A, Watters, Andrea, Brafford, Patricia, Krepler, Clemens, Godok, Tetiana, Li, Haiyin, Bonilla del Rio, Zuriñe, Zieseniss, Anke, Katschinski, Dörthe M, Sertel, Sinem M, Rizzoli, Silvio O, Garman, Bradley, Nathanson, Katherine L, Xu, Xiaowei, Chen, Qing, Oswald, Jack H, Lotem, Michal, Mills, Gordon B, Davies, Michael A, Schön, Michael P, Bogeski, Ivan, Herlyn, Meenhard, Vultur, Adina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Basic and Translational Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076948/
https://www.ncbi.nlm.nih.gov/pubmed/36054930
http://dx.doi.org/10.1093/neuonc/noac212

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