Cargando…
Modular and Computational Access to Innocuous Multistep Metal-Free Synthesis of 1,3,4-Oxadiazoles as Enzyme Inhibitors
[Image: see text] An array of 1,3,4-oxadiazole hybrids, 7a–s, structurally intriguing cores with potential in natural product synthesis and drug discovery, have been synthesized using innovative comparable conventional and microwave-assisted protocols. The synthesis was performed by the reaction of...
Autores principales: | Umair, Muhammad, Rehman, Aziz ur, Abbasi, Muhammad Athar, Siddiqui, Sabahat Zahra, Iqbal, Javed, Khalid, Hira, Rasool, Shahid, Khan, Shafi Ullah, Zafar, Fatiqa |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077450/ https://www.ncbi.nlm.nih.gov/pubmed/37033856 http://dx.doi.org/10.1021/acsomega.2c07612 |
Ejemplares similares
-
Novel Bi-heterocycles as Potent Inhibitors of Urease and Less Cytotoxic Agents: 3-({5-((2-Amino-1,3-thiazol-4-yl)methyl)-1,3,4-oxadiazol-2-yl}sulfanyl)-N-(un/substituted-phenyl)propanamides
por: Abbasi, Muhammad Athar, et al.
Publicado: (2020) -
Molecular Docking, Computational, and Antithrombotic Studies of Novel 1,3,4-Oxadiazole Derivatives
por: Batool, Majda, et al.
Publicado: (2018) -
Novel indole based hybrid oxadiazole scaffolds with N-(substituted-phenyl)butanamides: synthesis, lineweaver–burk plot evaluation and binding analysis of potent urease inhibitors
por: Nazir, Majid, et al.
Publicado: (2018) -
Convergent synthesis, kinetics insight and allosteric computational ascriptions of thiazole-(5-aryl)oxadiazole hybrids embraced with propanamides as alkaline phosphatase inhibitors
por: Butt, Abdul Rehman Sadiq, et al.
Publicado: (2023) -
1,3,4-Oxadiazole Derivative Attenuates Chronic Constriction Injury Induced Neuropathic Pain: A Computational, Behavioral, and Molecular Approach
por: Faheem, Muhammad, et al.
Publicado: (2020)