CD163(+) macrophages restrain vascular calcification, promoting the development of high-risk plaque

Vascular calcification (VC) is concomitant with atherosclerosis, yet it remains uncertain why rupture-prone high-risk plaques do not typically show extensive calcification. Intraplaque hemorrhage (IPH) deposits erythrocyte-derived cholesterol, enlarging the necrotic core and promoting high-risk plaq...

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Detalles Bibliográficos
Autores principales: Sakamoto, Atsushi, Kawakami, Rika, Mori, Masayuki, Guo, Liang, Paek, Ka Hyun, Mosquera, Jose Verdezoto, Cornelissen, Anne, Ghosh, Saikat Kumar B., Kawai, Kenji, Konishi, Takao, Fernandez, Raquel, Fuller, Daniela T., Xu, Weili, Vozenilek, Aimee E., Sato, Yu, Jinnouchi, Hiroyuki, Torii, Sho, Turner, Adam W., Akahori, Hirokuni, Kuntz, Salome, Weinkauf, Craig C., Lee, Parker J., Kutys, Robert, Harris, Kathryn, Killey, Alfred Lawrence, Mayhew, Christina M., Ellis, Matthew, Weinstein, Leah M., Gadhoke, Neel V., Dhingra, Roma, Ullman, Jeremy, Dikongue, Armella, Romero, Maria E., Kolodgie, Frank D., Miller, Clint L., Virmani, Renu, Finn, Aloke V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077470/
https://www.ncbi.nlm.nih.gov/pubmed/36719758
http://dx.doi.org/10.1172/jci.insight.154922

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