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Parathyroid hormone 1 receptor signaling mediates breast cancer metastasis to bone in mice

Bone metastases are a common complication of breast cancer. We have demonstrated that intermittent administration of parathyroid hormone (PTH[1-34]) reduces the incidence of bone metastases in murine models of breast cancer by acting on osteoblasts to alter the bone microenvironment. Here, we examin...

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Detalles Bibliográficos
Autores principales: Swami, Srilatha, Zhu, Hui, Nisco, Aria, Kimura, Takaharu, Kim, Matthew J., Nair, Vaisakh, Wu, Joy Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077472/
https://www.ncbi.nlm.nih.gov/pubmed/36692956
http://dx.doi.org/10.1172/jci.insight.157390