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Parathyroid hormone 1 receptor signaling mediates breast cancer metastasis to bone in mice
Bone metastases are a common complication of breast cancer. We have demonstrated that intermittent administration of parathyroid hormone (PTH[1-34]) reduces the incidence of bone metastases in murine models of breast cancer by acting on osteoblasts to alter the bone microenvironment. Here, we examin...
Autores principales: | Swami, Srilatha, Zhu, Hui, Nisco, Aria, Kimura, Takaharu, Kim, Matthew J., Nair, Vaisakh, Wu, Joy Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077472/ https://www.ncbi.nlm.nih.gov/pubmed/36692956 http://dx.doi.org/10.1172/jci.insight.157390 |
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