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Derivation of a minimal functional XIST by combining human and mouse interaction domains

X-inactive specific transcript (XIST) is a 17–19 kb long non-coding ribonucleic acid (RNA) critical for X-chromosome inactivation. Tandem repeats within the RNA serve as functional domains involved in the cis-limited recruitment of heterochromatic changes and silencing. To explore the sufficiency of...

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Detalles Bibliográficos
Autores principales: Navarro-Cobos, Maria Jose, Morales-Guzman, Suria Itzel, Baldry, Sarah E L, Brown, Carolyn J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077506/
https://www.ncbi.nlm.nih.gov/pubmed/36426827
http://dx.doi.org/10.1093/hmg/ddac285

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