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Derivation of a minimal functional XIST by combining human and mouse interaction domains
X-inactive specific transcript (XIST) is a 17–19 kb long non-coding ribonucleic acid (RNA) critical for X-chromosome inactivation. Tandem repeats within the RNA serve as functional domains involved in the cis-limited recruitment of heterochromatic changes and silencing. To explore the sufficiency of...
Autores principales: | Navarro-Cobos, Maria Jose, Morales-Guzman, Suria Itzel, Baldry, Sarah E L, Brown, Carolyn J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077506/ https://www.ncbi.nlm.nih.gov/pubmed/36426827 http://dx.doi.org/10.1093/hmg/ddac285 |
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