Human TrkA(R649W) mutation impairs nociception, sweating and cognitive abilities: a mouse model of HSAN IV

A functional nerve growth factor NGF–Tropomyosin Receptor kinase A (TrkA) system is an essential requisite for the generation and maintenance of long-lasting thermal and mechanical hyperalgesia in adult mammals. Indeed, mutations in the gene encoding for TrkA are responsible for a rare condition, na...

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Detalles Bibliográficos
Autores principales: Pacifico, Paola, Testa, Giovanna, Amodeo, Rosy, Mainardi, Marco, Tiberi, Alexia, Convertino, Domenica, Arevalo, Juan Carlos, Marchetti, Laura, Costa, Mario, Cattaneo, Antonino, Capsoni, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077510/
https://www.ncbi.nlm.nih.gov/pubmed/36537577
http://dx.doi.org/10.1093/hmg/ddac295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077510/
https://www.ncbi.nlm.nih.gov/pubmed/36537577
http://dx.doi.org/10.1093/hmg/ddac295

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