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Cost-Effective Pipeline for a Rational Design and Selection of Capsaicin Analogues Targeting TRPV1 Channels

[Image: see text] Transient receptor potential (TRP) channels constitute a large group of membrane receptors associated with sensory pathways in vertebrates. One of the most studied is TRPV1, a polymodal receptor tuned for detecting heat and pungent compounds. Specific inhibition of the nociceptive...

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Detalles Bibliográficos
Autores principales: Bustos, Daniel, Galarza, Christian, Ordoñez, Wilson, Brauchi, Sebastian, Benso, Bruna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077575/
https://www.ncbi.nlm.nih.gov/pubmed/37033853
http://dx.doi.org/10.1021/acsomega.2c05672

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