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Protocatechuic aldehyde acts synergistically with dacarbazine to augment DNA double-strand breaks and promote apoptosis in cutaneous melanoma cells
BACKGROUND: Despite rapid developments in immunotherapy and targeted therapy, dacarbazine (DTIC)-based chemotherapy still has been placed at the first-line for advanced melanoma patients who are after failure of immunotherapy or targeted therapy. However, the limited response rate and survival benef...
Autores principales: | Pei, Junxia, Su, Zhou, Zeng, Xin, Zhong, Ya, Zhang, Yamei, Yang, Yixi, Lu, Qiuxia, Li, Jian, Deng, Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077623/ https://www.ncbi.nlm.nih.gov/pubmed/37024907 http://dx.doi.org/10.1186/s12906-023-03933-w |
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