Necrotizing Soft Tissue Infections in South Australia: A 15-Year Review

Necrotizing soft tissue infections (NSTIs) are associated with high morbidity and mortality. We retrospectively examined the impact of empiric antimicrobials coupled with early surgery on mortality in NSTI. Early surgery independently reduced 30-day mortality (odds ratio, .16; 95% confidence interva...

Descripción completa

Detalles Bibliográficos
Autores principales: Tam, Patrick Chung Kay, Kennedy, Brendan, Ashokan, Anushia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077820/
https://www.ncbi.nlm.nih.gov/pubmed/37035499
http://dx.doi.org/10.1093/ofid/ofad117
_version_ 1785020388129898496
author Tam, Patrick Chung Kay
Kennedy, Brendan
Ashokan, Anushia
author_facet Tam, Patrick Chung Kay
Kennedy, Brendan
Ashokan, Anushia
author_sort Tam, Patrick Chung Kay
collection PubMed
description Necrotizing soft tissue infections (NSTIs) are associated with high morbidity and mortality. We retrospectively examined the impact of empiric antimicrobials coupled with early surgery on mortality in NSTI. Early surgery independently reduced 30-day mortality (odds ratio, .16; 95% confidence interval, .05–.51; P < .001) that was not further augmented by empiric antimicrobial choice.
format Online
Article
Text
id pubmed-10077820
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-100778202023-04-07 Necrotizing Soft Tissue Infections in South Australia: A 15-Year Review Tam, Patrick Chung Kay Kennedy, Brendan Ashokan, Anushia Open Forum Infect Dis Brief Report Necrotizing soft tissue infections (NSTIs) are associated with high morbidity and mortality. We retrospectively examined the impact of empiric antimicrobials coupled with early surgery on mortality in NSTI. Early surgery independently reduced 30-day mortality (odds ratio, .16; 95% confidence interval, .05–.51; P < .001) that was not further augmented by empiric antimicrobial choice. Oxford University Press 2023-03-04 /pmc/articles/PMC10077820/ /pubmed/37035499 http://dx.doi.org/10.1093/ofid/ofad117 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Tam, Patrick Chung Kay
Kennedy, Brendan
Ashokan, Anushia
Necrotizing Soft Tissue Infections in South Australia: A 15-Year Review
title Necrotizing Soft Tissue Infections in South Australia: A 15-Year Review
title_full Necrotizing Soft Tissue Infections in South Australia: A 15-Year Review
title_fullStr Necrotizing Soft Tissue Infections in South Australia: A 15-Year Review
title_full_unstemmed Necrotizing Soft Tissue Infections in South Australia: A 15-Year Review
title_short Necrotizing Soft Tissue Infections in South Australia: A 15-Year Review
title_sort necrotizing soft tissue infections in south australia: a 15-year review
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10077820/
https://www.ncbi.nlm.nih.gov/pubmed/37035499
http://dx.doi.org/10.1093/ofid/ofad117
work_keys_str_mv AT tampatrickchungkay necrotizingsofttissueinfectionsinsouthaustraliaa15yearreview
AT kennedybrendan necrotizingsofttissueinfectionsinsouthaustraliaa15yearreview
AT ashokananushia necrotizingsofttissueinfectionsinsouthaustraliaa15yearreview

Ejemplares similares