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Tetraethylammonium block of water flux in Aquaporin-1 channels expressed in kidney thin limbs of Henle's loop and a kidney-derived cell line.

BACKGROUND: Aquaporin-1 (AQP1) channels are constitutively active water channels that allow rapid transmembrane osmotic water flux, and also serve as cyclic-GMP-gated ion channels. Tetraethylammonium chloride (TEA; 0.05 to 10 mM) was shown previously to inhibit the osmotic water permeability of huma...

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Detalles Bibliográficos
Autores principales: Yool, Andrea J, Brokl, Olga H, Pannabecker, Thomas L, Dantzler, William H, Stamer, W Daniel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC100781/
https://www.ncbi.nlm.nih.gov/pubmed/11914159