Cargando…

Ginsenoside Rg1 treatment alleviates renal fibrosis by inhibiting the NOX4–MAPK pathway in T2DM mice

Diabetic kidney disease (DKD) is a severe complication of type 2 diabetes mellitus (T2DM). However, the pathogenesis of DKD remains unclear, and effective treatment strategies are still lacking. Ginsenoside Rg1 (Rg1) has been reported to improve DKD, but the mechanism is unclear. NADPH oxidase 4 (NO...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ji, Pengmin, Shi, Qifeng, Liu, Yan, Han, Min, Su, Yong, Sun, Ran, Zhou, Huimin, Li, Weizu, Li, Weiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2023
Materias:	Clinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078147/ https://www.ncbi.nlm.nih.gov/pubmed/37017270 http://dx.doi.org/10.1080/0886022X.2023.2197075

Ejemplares similares

Ginsenoside Rg1 treatment protects against cognitive dysfunction via inhibiting PLC–CN–NFAT1 signaling in T2DM mice
por: Dong, Xianan, et al.
Publicado: (2023)

Ginsenoside Rg1 alleviates learning and memory impairments and Aβ disposition through inhibiting NLRP1 inflammasome and autophagy dysfunction in APP/PS1 mice
por: Li, Xuewang, et al.
Publicado: (2022)

Ginsenoside Rg1 ameliorates aging-induced liver fibrosis by inhibiting the NOX4/NLRP3 inflammasome in SAMP8 mice
por: Li, Yan, et al.
Publicado: (2021)

Ginsenoside Rg1 alleviates Aβ deposition by inhibiting NADPH oxidase 2 activation in APP/PS1 mice
por: Zhang, Han, et al.
Publicado: (2021)

Ginsenoside Rg1 attenuates cerebral ischemia-reperfusion injury due to inhibition of NOX2-mediated calcium homeostasis dysregulation in mice
por: Han, Yuli, et al.
Publicado: (2022)

Ginsenoside Rg1 alleviates lipopolysaccharide-induced neuronal damage by inhibiting NLRP1 inflammasomes in HT22 cells
por: Zhang, Yaodong, et al.
Publicado: (2021)

Ginsenoside Rg1 protects against neuronal degeneration induced by chronic dexamethasone treatment by inhibiting NLRP-1 inflammasomes in mice
por: Zhang, Yaodong, et al.
Publicado: (2017)

Ginsenoside Rg2 alleviates myocardial fibrosis by regulating TGF-β1/Smad signalling pathway
por: Wang, Quanwei, et al.
Publicado: (2021)

Ginsenoside Rg3 attenuates pulmonary fibrosis by inhibiting endothelial to mesenchymal transition
por: Yun, Eunsik, et al.
Publicado: (2023)

Comparative Pharmacokinetics of Ginsenoside Rg(3) and Ginsenoside Rh(2) after Oral Administration of Ginsenoside Rg(3) in Normal and Walker 256 Tumor-bearing Rats
por: Fan, He, et al.
Publicado: (2016)

Ginsenoside Rg3 Alleviates Antithyroid Cancer Drug Vandetanib-Induced QT Interval Prolongation
por: Zhang, Juan, et al.
Publicado: (2021)

Ginsenoside Rg1 alleviates repeated alcohol exposure-induced psychomotor and cognitive deficits
por: Huang, Lu, et al.
Publicado: (2020)

Pharmacological activities of ginsenoside Rg5 (Review)
por: Liu, Ming-Yang, et al.
Publicado: (2021)

Ginsenoside Rg2 inhibits osteoclastogenesis by downregulating the NFATc1, c-Fos, and MAPK pathways
por: Lee, Sung-Hoon, et al.
Publicado: (2023)

Ginsenoside Rg1 and Re alleviates inflammatory responses and oxidative stress of broiler chicks challenged by lipopolysaccharide
por: Hu, Weidong, et al.
Publicado: (2023)

Protective effect and mechanism of ginsenoside Rg2 on atherosclerosis
por: Xue, Qianqian, et al.
Publicado: (2023)

Anti-Angiogenic Properties of Ginsenoside Rg3
por: Nakhjavani, Maryam, et al.
Publicado: (2020)

Ginsenoside Rg3 Alleviates Lipopolysaccharide-Induced Learning and Memory Impairments by Anti-Inflammatory Activity in Rats
por: Lee, Bombi, et al.
Publicado: (2013)

Ginsenoside Rg1 Alleviates Acute Ulcerative Colitis by Modulating Gut Microbiota and Microbial Tryptophan Metabolism
por: Cheng, Hao, et al.
Publicado: (2022)

Molecular signaling of ginsenosides Rb1, Rg1, and Rg3 and their mode of actions
por: Mohanan, Padmanaban, et al.
Publicado: (2018)

Ginsenoside Rg3 inhibits pulmonary fibrosis by preventing HIF-1α nuclear localisation
por: Fu, Zhuo, et al.
Publicado: (2021)

Tamibarotene inhibit the accumulation of fibrocyte and alleviate renal fibrosis by IL-17A
por: Li, Lixi, et al.
Publicado: (2020)

Protective effect of ginsenoside Rg1 on lidocaine-induced apoptosis
por: LI, HUI, et al.
Publicado: (2014)

Ginsenoside Rg1 Epigenetically Modulates Smad7 Expression in Liver Fibrosis via MicroRNA-152
por: Zhang, Rongrong, et al.
Publicado: (2023)

Relationship Between Ginsenoside Rg3 and Metabolic Syndrome
por: Lee, Hyunji, et al.
Publicado: (2020)

Ginsenoside Rg1 Alleviates Hepatic Ischemia-Reperfusion Injury in Mice via Activating ERα-Regulating YAP Expression
por: Zhang, Kehui, et al.
Publicado: (2021)

A systematic review and meta-analysis of Ginsenoside-Rg1 (G-Rg1) in experimental ischemic stroke
por: Xie, Cheng-long, et al.
Publicado: (2015)

The anxiolytic-like effects of ginsenoside Rg3 on chronic unpredictable stress in rats
por: Xu, Jia-ning, et al.
Publicado: (2018)

Ginsenoside Rg3 has effects comparable to those of ginsenoside re on diabetic kidney disease prevention in db/db mice by regulating inflammation, fibrosis and PPARγ
por: Sui, Zhe, et al.
Publicado: (2023)

Kinetic study for the optimization of ginsenoside Rg3 production by heat treatment of ginsenoside Rb1
por: Vo, Hoang Tung, et al.
Publicado: (2015)

Preclinical systematic review of ginsenoside Rg1 for cognitive impairment in Alzheimer’s disease
por: Liang, Hai-Yong, et al.
Publicado: (2021)

Ginsenoside Rg3 Suppresses Proliferation and Induces Apoptosis in Human Osteosarcoma
por: Li, Yi, et al.
Publicado: (2018)

Neuroprotective effects of ginsenosides Rh(1 )and Rg(2 )on neuronal cells
por: Li, Xiao-Fan, et al.
Publicado: (2011)

Ginsenoside Rg1 and 20(S)-Rg3 Induce IgA Production by Mouse B Cells
por: Park, Ha-Yan, et al.
Publicado: (2015)

Ginsenoside Rg3-induced EGFR/MAPK pathway deactivation inhibits melanoma cell proliferation by decreasing FUT4/LeY expression
por: Shan, Xiu, et al.
Publicado: (2015)

Effects of Ginsenosides Rg1 on Osteoblasts Cultured with Ti Particles
por: Lin, Yu, et al.
Publicado: (2012)

Inhibition of in vitro Tumor Cell Invasion by Ginsenoside Rg(3)
por: Shinkai, Kiyoko, et al.
Publicado: (1996)

Upregulation of autophagy by Ginsenoside Rg2 in MCF-7 cells
por: Chung, Yuheon, et al.
Publicado: (2018)

Ginsenoside Rg3 inhibits the biological activity of SGC‐7901
por: Yang, Qing, et al.
Publicado: (2020)

Ginsenoside Rg1 as an Effective Regulator of Mesenchymal Stem Cells
por: He, Fang, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_qtrvdb3rvgo6495j5o4g8qf24l