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Defining the separation landscape of topological domains for decoding consensus domain organization of the 3D genome

Topologically associating domains (TADs) have emerged as basic structural and functional units of genome organization and have been determined by many computational methods from Hi-C contact maps. However, the TADs obtained by different methods vary greatly, which makes the accurate determination of...

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Detalles Bibliográficos
Autores principales: Dang, Dachang, Zhang, Shao-Wu, Duan, Ran, Zhang, Shihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078287/
https://www.ncbi.nlm.nih.gov/pubmed/36894325
http://dx.doi.org/10.1101/gr.277187.122