The impact of SWI/SNF and NuRD inactivation on gene expression is tightly coupled with levels of RNA polymerase II occupancy at promoters

SWI/SNF and NuRD are protein complexes that antagonistically regulate DNA accessibility. However, repression of their activities often leads to unanticipated changes in target gene expression (paradoxical), highlighting our incomplete understanding of their activities. Here we show that SWI/SNF and...

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Detalles Bibliográficos
Autores principales: Pundhir, Sachin, Su, Jinyu, Tapia, Marta, Hansen, Anne Meldgaard, Haile, James Seymour, Hansen, Klaus, Porse, Bo Torben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078288/
https://www.ncbi.nlm.nih.gov/pubmed/36927987
http://dx.doi.org/10.1101/gr.277089.122

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