Hepatocyte-specific knockout of HIF-2α cannot alleviate carbon tetrachloride-induced liver fibrosis in mice

BACKGROUND: The effects of hypoxia inducible factor-2α (HIF-2α) deficiency on liver fibrosis have not been demonstrated in a fibrosis model induced by carbon tetrachloride (CCl(4)). We aimed to examine whether hepatocyte-specific HIF-2α deletion could ameliorate CCl(4)-induced liver fibrosis in mice...

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Detalles Bibliográficos
Autores principales: Ye, Jianfang, Chen, Jie, Li, Yun, Sun, Liao, Lu, Hongyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078453/
https://www.ncbi.nlm.nih.gov/pubmed/37033734
http://dx.doi.org/10.7717/peerj.15191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078453/
https://www.ncbi.nlm.nih.gov/pubmed/37033734
http://dx.doi.org/10.7717/peerj.15191

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