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The effect of specific bioactive collagen peptides on function and muscle remodeling during human resistance training
AIM: Bioactive collagen peptides (CP) have been suggested to augment the functional, structural (size and architecture), and contractile adaptations of skeletal muscle to resistance training (RT), but with limited evidence. This study aimed to determine if CP vs. placebo (PLA) supplementation enhanc...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078466/ https://www.ncbi.nlm.nih.gov/pubmed/36433662 http://dx.doi.org/10.1111/apha.13903 |
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author | Balshaw, Thomas G. Funnell, Mark P. McDermott, Emmet Maden‐Wilkinson, Thomas M. Abela, Sean Quteishat, Btool Edsey, Max James, Lewis J. Folland, Jonathan P. |
author_facet | Balshaw, Thomas G. Funnell, Mark P. McDermott, Emmet Maden‐Wilkinson, Thomas M. Abela, Sean Quteishat, Btool Edsey, Max James, Lewis J. Folland, Jonathan P. |
author_sort | Balshaw, Thomas G. |
collection | PubMed |
description | AIM: Bioactive collagen peptides (CP) have been suggested to augment the functional, structural (size and architecture), and contractile adaptations of skeletal muscle to resistance training (RT), but with limited evidence. This study aimed to determine if CP vs. placebo (PLA) supplementation enhanced the functional and underpinning structural, and contractile adaptations after 15 weeks of lower body RT. METHODS: Young healthy males were randomized to consume either 15 g of CP (n = 19) or PLA (n = 20) once every day during a standardized program of progressive knee extensor, knee flexor, and hip extensor RT 3 times/wk. Measurements pre‐ and post‐RT included: knee extensor and flexor isometric strength; quadriceps, hamstrings, and gluteus maximus volume with MRI; evoked twitch contractions, 1RM lifting strength, and architecture (with ultrasound) of the quadriceps. RESULTS: Percentage changes in maximum strength (isometric or 1RM) did not differ between‐groups (0.684 ≤ p ≤ 0.929). Increases in muscle volume were greater (quadriceps 15.2% vs. 10.3%; vastus medialis (VM) 15.6% vs. 9.7%; total muscle volume 15.7% vs. 11.4%; [all] p ≤ 0.032) or tended to be greater (hamstring 16.5% vs. 12.8%; gluteus maximus 16.6% vs. 12.9%; 0.089 ≤ p ≤ 0.091) for CP vs. PLA. There were also greater increases in twitch peak torque (22.3% vs. 12.3%; p = 0.038) and angle of pennation of the VM (16.8% vs. 5.8%, p = 0.046), but not other muscles, for CP vs. PLA. CONCLUSIONS: CP supplementation produced a cluster of consistent effects indicating greater skeletal muscle remodeling with RT compared to PLA. Notably, CP supplementation amplified the quadriceps and total muscle volume increases induced by RT. |
format | Online Article Text |
id | pubmed-10078466 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-100784662023-04-07 The effect of specific bioactive collagen peptides on function and muscle remodeling during human resistance training Balshaw, Thomas G. Funnell, Mark P. McDermott, Emmet Maden‐Wilkinson, Thomas M. Abela, Sean Quteishat, Btool Edsey, Max James, Lewis J. Folland, Jonathan P. Acta Physiol (Oxf) Research Papers AIM: Bioactive collagen peptides (CP) have been suggested to augment the functional, structural (size and architecture), and contractile adaptations of skeletal muscle to resistance training (RT), but with limited evidence. This study aimed to determine if CP vs. placebo (PLA) supplementation enhanced the functional and underpinning structural, and contractile adaptations after 15 weeks of lower body RT. METHODS: Young healthy males were randomized to consume either 15 g of CP (n = 19) or PLA (n = 20) once every day during a standardized program of progressive knee extensor, knee flexor, and hip extensor RT 3 times/wk. Measurements pre‐ and post‐RT included: knee extensor and flexor isometric strength; quadriceps, hamstrings, and gluteus maximus volume with MRI; evoked twitch contractions, 1RM lifting strength, and architecture (with ultrasound) of the quadriceps. RESULTS: Percentage changes in maximum strength (isometric or 1RM) did not differ between‐groups (0.684 ≤ p ≤ 0.929). Increases in muscle volume were greater (quadriceps 15.2% vs. 10.3%; vastus medialis (VM) 15.6% vs. 9.7%; total muscle volume 15.7% vs. 11.4%; [all] p ≤ 0.032) or tended to be greater (hamstring 16.5% vs. 12.8%; gluteus maximus 16.6% vs. 12.9%; 0.089 ≤ p ≤ 0.091) for CP vs. PLA. There were also greater increases in twitch peak torque (22.3% vs. 12.3%; p = 0.038) and angle of pennation of the VM (16.8% vs. 5.8%, p = 0.046), but not other muscles, for CP vs. PLA. CONCLUSIONS: CP supplementation produced a cluster of consistent effects indicating greater skeletal muscle remodeling with RT compared to PLA. Notably, CP supplementation amplified the quadriceps and total muscle volume increases induced by RT. John Wiley and Sons Inc. 2022-12-13 2023-02 /pmc/articles/PMC10078466/ /pubmed/36433662 http://dx.doi.org/10.1111/apha.13903 Text en © 2022 The Authors. Acta Physiologica published by John Wiley & Sons Ltd on behalf of Scandinavian Physiological Society. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Research Papers Balshaw, Thomas G. Funnell, Mark P. McDermott, Emmet Maden‐Wilkinson, Thomas M. Abela, Sean Quteishat, Btool Edsey, Max James, Lewis J. Folland, Jonathan P. The effect of specific bioactive collagen peptides on function and muscle remodeling during human resistance training |
title | The effect of specific bioactive collagen peptides on function and muscle remodeling during human resistance training |
title_full | The effect of specific bioactive collagen peptides on function and muscle remodeling during human resistance training |
title_fullStr | The effect of specific bioactive collagen peptides on function and muscle remodeling during human resistance training |
title_full_unstemmed | The effect of specific bioactive collagen peptides on function and muscle remodeling during human resistance training |
title_short | The effect of specific bioactive collagen peptides on function and muscle remodeling during human resistance training |
title_sort | effect of specific bioactive collagen peptides on function and muscle remodeling during human resistance training |
topic | Research Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078466/ https://www.ncbi.nlm.nih.gov/pubmed/36433662 http://dx.doi.org/10.1111/apha.13903 |
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