Glucocorticoid mediated inhibition of LKB1 mutant non-small cell lung cancers

The glucocorticoid receptor (GR) is an important anti-cancer target in lymphoid cancers but has been understudied in solid tumors like lung cancer, although glucocorticoids are often given with chemotherapy regimens to mitigate side effects. Here, we identify a dexamethasone-GR mediated anti-cancer...

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Detalles Bibliográficos
Autores principales: Huffman, Kenneth E., Li, Long Shan, Carstens, Ryan, Park, Hyunsil, Girard, Luc, Avila, Kimberley, Wei, Shuguang, Kollipara, Rahul, Timmons, Brenda, Sudderth, Jessica, Bendris, Nawal, Kim, Jiyeon, Villalobos, Pamela, Fujimoto, Junya, Schmid, Sandra, Deberardinis, Ralph J., Wistuba, Ignacio, Heymach, John, Kittler, Ralf, Akbay, Esra A., Posner, Bruce, Wang, Yuzhuo, Lam, Stephen, Kliewer, Steven A., Mangelsdorf, David J., Minna, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078807/
https://www.ncbi.nlm.nih.gov/pubmed/37035141
http://dx.doi.org/10.3389/fonc.2023.1025443

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