Cargando…

Seroprevalence of Toxoplasmosis in Puerperal Women Treated at a Tertiary Referral Hospital

Objective  To evaluate the seroprevalence of toxoplasmosis among puerperal women cared for at a tertiary university hospital and the level of understanding of these puerperal women about toxoplasmosis, vertical transmission, and its prophylaxis. Methods  For this cross-sectional study, we evaluated...

Descripción completa

Detalles Bibliográficos
Autores principales: Medeiros, Juliana Fernandes, Rabelo e Silva, Ana Cláudia, Rocha, Natália Domene Franco da, Georg, Alexia Viegas, Melli, Patricia Pereira dos Santos, Quintana, Silvana Maria, Duarte, Geraldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Revinter Publicações Ltda. 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078889/
https://www.ncbi.nlm.nih.gov/pubmed/36977402
http://dx.doi.org/10.1055/s-0043-1764495
_version_ 1785020613063081984
author Medeiros, Juliana Fernandes
Rabelo e Silva, Ana Cláudia
Rocha, Natália Domene Franco da
Georg, Alexia Viegas
Melli, Patricia Pereira dos Santos
Quintana, Silvana Maria
Duarte, Geraldo
author_facet Medeiros, Juliana Fernandes
Rabelo e Silva, Ana Cláudia
Rocha, Natália Domene Franco da
Georg, Alexia Viegas
Melli, Patricia Pereira dos Santos
Quintana, Silvana Maria
Duarte, Geraldo
author_sort Medeiros, Juliana Fernandes
collection PubMed
description Objective  To evaluate the seroprevalence of toxoplasmosis among puerperal women cared for at a tertiary university hospital and the level of understanding of these puerperal women about toxoplasmosis, vertical transmission, and its prophylaxis. Methods  For this cross-sectional study, we evaluated 225 patients using presential interviews, prenatal documentation, and electronic medical records. Data were stored using Research Electronic Data Capture (REDCap) software. Prevalence rates were estimated by the presence of reactive IgG antibodies against Toxoplasma gondii . Data analysis was performed using the chi-square test and calculation of the odds ratio (OR). Seroreactivity to T. gondii and exposure variables (age, educational level, and parity) were analyzed using a confidence interval (95%CI) and a significance level of 5% (p < 0.05). Results  The seropositivity rate for T. gondii was 40%. There was no association between seroprevalence and age. Primiparity was a protective factor against seropositivity and low education was a risk factor. Conclusion  Knowledge of T. gondii infection and its transmission forms was significantly limited, presenting a risk for acute maternal toxoplasmosis and vertical transmission of this protozoan. Increasing the education level regarding the risk of toxoplasmosis during pregnancy could reduce the rates of infection and vertical transmission of this parasite.
format Online
Article
Text
id pubmed-10078889
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Thieme Revinter Publicações Ltda.
record_format MEDLINE/PubMed
spelling pubmed-100788892023-07-27 Seroprevalence of Toxoplasmosis in Puerperal Women Treated at a Tertiary Referral Hospital Medeiros, Juliana Fernandes Rabelo e Silva, Ana Cláudia Rocha, Natália Domene Franco da Georg, Alexia Viegas Melli, Patricia Pereira dos Santos Quintana, Silvana Maria Duarte, Geraldo Rev Bras Ginecol Obstet Objective  To evaluate the seroprevalence of toxoplasmosis among puerperal women cared for at a tertiary university hospital and the level of understanding of these puerperal women about toxoplasmosis, vertical transmission, and its prophylaxis. Methods  For this cross-sectional study, we evaluated 225 patients using presential interviews, prenatal documentation, and electronic medical records. Data were stored using Research Electronic Data Capture (REDCap) software. Prevalence rates were estimated by the presence of reactive IgG antibodies against Toxoplasma gondii . Data analysis was performed using the chi-square test and calculation of the odds ratio (OR). Seroreactivity to T. gondii and exposure variables (age, educational level, and parity) were analyzed using a confidence interval (95%CI) and a significance level of 5% (p < 0.05). Results  The seropositivity rate for T. gondii was 40%. There was no association between seroprevalence and age. Primiparity was a protective factor against seropositivity and low education was a risk factor. Conclusion  Knowledge of T. gondii infection and its transmission forms was significantly limited, presenting a risk for acute maternal toxoplasmosis and vertical transmission of this protozoan. Increasing the education level regarding the risk of toxoplasmosis during pregnancy could reduce the rates of infection and vertical transmission of this parasite. Thieme Revinter Publicações Ltda. 2023-03-28 /pmc/articles/PMC10078889/ /pubmed/36977402 http://dx.doi.org/10.1055/s-0043-1764495 Text en Federação Brasileira de Ginecologia e Obstetrícia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. ( https://creativecommons.org/licenses/by/4.0/ ) https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Medeiros, Juliana Fernandes
Rabelo e Silva, Ana Cláudia
Rocha, Natália Domene Franco da
Georg, Alexia Viegas
Melli, Patricia Pereira dos Santos
Quintana, Silvana Maria
Duarte, Geraldo
Seroprevalence of Toxoplasmosis in Puerperal Women Treated at a Tertiary Referral Hospital
title Seroprevalence of Toxoplasmosis in Puerperal Women Treated at a Tertiary Referral Hospital
title_full Seroprevalence of Toxoplasmosis in Puerperal Women Treated at a Tertiary Referral Hospital
title_fullStr Seroprevalence of Toxoplasmosis in Puerperal Women Treated at a Tertiary Referral Hospital
title_full_unstemmed Seroprevalence of Toxoplasmosis in Puerperal Women Treated at a Tertiary Referral Hospital
title_short Seroprevalence of Toxoplasmosis in Puerperal Women Treated at a Tertiary Referral Hospital
title_sort seroprevalence of toxoplasmosis in puerperal women treated at a tertiary referral hospital
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078889/
https://www.ncbi.nlm.nih.gov/pubmed/36977402
http://dx.doi.org/10.1055/s-0043-1764495
work_keys_str_mv AT medeirosjulianafernandes seroprevalenceoftoxoplasmosisinpuerperalwomentreatedatatertiaryreferralhospital
AT rabeloesilvaanaclaudia seroprevalenceoftoxoplasmosisinpuerperalwomentreatedatatertiaryreferralhospital
AT rochanataliadomenefrancoda seroprevalenceoftoxoplasmosisinpuerperalwomentreatedatatertiaryreferralhospital
AT georgalexiaviegas seroprevalenceoftoxoplasmosisinpuerperalwomentreatedatatertiaryreferralhospital
AT mellipatriciapereiradossantos seroprevalenceoftoxoplasmosisinpuerperalwomentreatedatatertiaryreferralhospital
AT quintanasilvanamaria seroprevalenceoftoxoplasmosisinpuerperalwomentreatedatatertiaryreferralhospital
AT duartegeraldo seroprevalenceoftoxoplasmosisinpuerperalwomentreatedatatertiaryreferralhospital