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KRAS: Druggable at Last
The approval of adagrasib for non–small cell lung cancer is a milestone in drug development. This commentary highlights the history of the research that led to this breakthrough that will help many patients with KRAS-mutated cancers to live longer and better.
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078900/ https://www.ncbi.nlm.nih.gov/pubmed/36933199 http://dx.doi.org/10.1093/oncolo/oyad014 |
_version_ | 1785020615831322624 |
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author | Herzberg, Benjamin O Manji, Gulam A |
author_facet | Herzberg, Benjamin O Manji, Gulam A |
author_sort | Herzberg, Benjamin O |
collection | PubMed |
description | The approval of adagrasib for non–small cell lung cancer is a milestone in drug development. This commentary highlights the history of the research that led to this breakthrough that will help many patients with KRAS-mutated cancers to live longer and better. |
format | Online Article Text |
id | pubmed-10078900 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-100789002023-04-07 KRAS: Druggable at Last Herzberg, Benjamin O Manji, Gulam A Oncologist Commentaries The approval of adagrasib for non–small cell lung cancer is a milestone in drug development. This commentary highlights the history of the research that led to this breakthrough that will help many patients with KRAS-mutated cancers to live longer and better. Oxford University Press 2023-03-18 /pmc/articles/PMC10078900/ /pubmed/36933199 http://dx.doi.org/10.1093/oncolo/oyad014 Text en © The Author(s) 2023. Published by Oxford University Press. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Commentaries Herzberg, Benjamin O Manji, Gulam A KRAS: Druggable at Last |
title |
KRAS: Druggable at Last |
title_full |
KRAS: Druggable at Last |
title_fullStr |
KRAS: Druggable at Last |
title_full_unstemmed |
KRAS: Druggable at Last |
title_short |
KRAS: Druggable at Last |
title_sort | kras: druggable at last |
topic | Commentaries |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078900/ https://www.ncbi.nlm.nih.gov/pubmed/36933199 http://dx.doi.org/10.1093/oncolo/oyad014 |
work_keys_str_mv | AT herzbergbenjamino krasdruggableatlast AT manjigulama krasdruggableatlast |