Activity of Anlotinib in the Second-Line Therapy of Metastatic Gastrointestinal Stromal Tumors: A Prospective, Multicenter, In Vitro Study

BACKGROUND: Anlotinib is a multi-target tyrosine kinase inhibitor that can effectively inhibit tumor cell proliferation after receptor kinase activation caused by KIT gene mutation. METHODS: We tested the inhibitory effect of anlotinib in GIST cell lines with different gene mutations and evaluated t...

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Detalles Bibliográficos
Autores principales: Zhou, Yongjian, Zeng, Chunling, Sun, Xiaofeng, Zhang, Jun, Qu, Hongyan, Zhang, Xinhua, Zhou, Ye, Liu, Zimin, Wu, Xiaojun, Wu, Xin, Jiao, Xuelong, Shen, Lin, Zhou, Yanbing, Wang, Yuexiang, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Gastrointestinal Cancer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078906/
https://www.ncbi.nlm.nih.gov/pubmed/36779523
http://dx.doi.org/10.1093/oncolo/oyac271

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