Mutation-Agnostic Detection of Colorectal Cancer Using Liquid Biopsy-Based Methylation-Specific Signatures

Detection of methylation patterns in circulating tumor DNA (ctDNA) can offer a novel approach for cancer diagnostics given the unique signature for each tumor type. We developed a next-generation sequencing (NGS)-based assay targeting 32 CpG sites to detect colorectal cancer-specific ctDNA. NGS was...

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Detalles Bibliográficos
Autores principales: Gouda, Mohamed A, Duose, Dzifa Y, Lapin, Morten, Zalles, Stephanie, Huang, Helen J, Xi, Yuanxin, Zheng, Xiaofeng, Aldesoky, Amira I, Alhanafy, Alshimaa M, Shehata, Mohamed A, Wang, Jing, Kopetz, Scott, Meric-Bernstam, Funda, Wistuba, Ignacio I, Luthra, Rajyalakshmi, Janku, Filip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Brief Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078907/
https://www.ncbi.nlm.nih.gov/pubmed/36200910
http://dx.doi.org/10.1093/oncolo/oyac204

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