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Combined therapy with methotrexate nanoconjugate and dendritic cells with downregulated IL-10R expression modulates the tumor microenvironment and enhances the systemic anti-tumor immune response in MC38 murine colon carcinoma

BACKGROUND: Understanding the negative impact of the tumor microenvironment on the creation of an effective immune response has contributed to the development of new therapeutic anti-cancer strategies. One such solution is combined therapy consisting of chemotherapeutic administration followed by de...

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Detalles Bibliográficos
Autores principales:	Szczygieł, Agnieszka, Węgierek-Ciura, Katarzyna, Wróblewska, Anna, Mierzejewska, Jagoda, Rossowska, Joanna, Szermer-Olearnik, Bożena, Świtalska, Marta, Anger-Góra, Natalia, Goszczyński, Tomasz M., Pajtasz-Piasecka, Elżbieta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078943/ https://www.ncbi.nlm.nih.gov/pubmed/37033926 http://dx.doi.org/10.3389/fimmu.2023.1155377

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