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Influences of human thorax variability on population rib fracture risk prediction using human body models

Rib fractures remain a common injury for vehicle occupants in crashes. The risk of a human sustaining rib fractures from thorax loading is highly variable, potentially due to a variability in individual factors such as material properties and geometry of the ribs and ribcage. Human body models (HBMs...

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Autores principales: Larsson, Karl-Johan, Iraeus, Johan, Holcombe, Sven, Pipkorn, Bengt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078960/
https://www.ncbi.nlm.nih.gov/pubmed/37034266
http://dx.doi.org/10.3389/fbioe.2023.1154272
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author Larsson, Karl-Johan
Iraeus, Johan
Holcombe, Sven
Pipkorn, Bengt
author_facet Larsson, Karl-Johan
Iraeus, Johan
Holcombe, Sven
Pipkorn, Bengt
author_sort Larsson, Karl-Johan
collection PubMed
description Rib fractures remain a common injury for vehicle occupants in crashes. The risk of a human sustaining rib fractures from thorax loading is highly variable, potentially due to a variability in individual factors such as material properties and geometry of the ribs and ribcage. Human body models (HBMs) with a detailed ribcage can be used as occupant substitutes to aid in the prediction of rib injury risk at the tissue level in crash analysis. To improve this capability, model parametrization can be used to represent human variability in simulation studies. The aim of this study was to identify the variations in the physical properties of the human thorax that have the most influence on rib fracture risk for the population of vehicle occupants. A total of 15 different geometrical and material factors, sourced from published literature, were varied in a parametrized SAFER HBM. Parametric sensitivity analyses were conducted for two crash configurations, frontal and near-side impacts. The results show that variability in rib cortical bone thickness, rib cortical bone material properties, and rib cross-sectional width had the greatest influence on the risk for an occupant to sustain two or more fractured ribs in both impacts. Therefore, it is recommended that these three parameters be included in rib fracture risk analysis with HBMs for the population of vehicle occupants.
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spelling pubmed-100789602023-04-07 Influences of human thorax variability on population rib fracture risk prediction using human body models Larsson, Karl-Johan Iraeus, Johan Holcombe, Sven Pipkorn, Bengt Front Bioeng Biotechnol Bioengineering and Biotechnology Rib fractures remain a common injury for vehicle occupants in crashes. The risk of a human sustaining rib fractures from thorax loading is highly variable, potentially due to a variability in individual factors such as material properties and geometry of the ribs and ribcage. Human body models (HBMs) with a detailed ribcage can be used as occupant substitutes to aid in the prediction of rib injury risk at the tissue level in crash analysis. To improve this capability, model parametrization can be used to represent human variability in simulation studies. The aim of this study was to identify the variations in the physical properties of the human thorax that have the most influence on rib fracture risk for the population of vehicle occupants. A total of 15 different geometrical and material factors, sourced from published literature, were varied in a parametrized SAFER HBM. Parametric sensitivity analyses were conducted for two crash configurations, frontal and near-side impacts. The results show that variability in rib cortical bone thickness, rib cortical bone material properties, and rib cross-sectional width had the greatest influence on the risk for an occupant to sustain two or more fractured ribs in both impacts. Therefore, it is recommended that these three parameters be included in rib fracture risk analysis with HBMs for the population of vehicle occupants. Frontiers Media S.A. 2023-03-23 /pmc/articles/PMC10078960/ /pubmed/37034266 http://dx.doi.org/10.3389/fbioe.2023.1154272 Text en Copyright © 2023 Larsson, Iraeus, Holcombe and Pipkorn. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Bioengineering and Biotechnology
Larsson, Karl-Johan
Iraeus, Johan
Holcombe, Sven
Pipkorn, Bengt
Influences of human thorax variability on population rib fracture risk prediction using human body models
title Influences of human thorax variability on population rib fracture risk prediction using human body models
title_full Influences of human thorax variability on population rib fracture risk prediction using human body models
title_fullStr Influences of human thorax variability on population rib fracture risk prediction using human body models
title_full_unstemmed Influences of human thorax variability on population rib fracture risk prediction using human body models
title_short Influences of human thorax variability on population rib fracture risk prediction using human body models
title_sort influences of human thorax variability on population rib fracture risk prediction using human body models
topic Bioengineering and Biotechnology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078960/
https://www.ncbi.nlm.nih.gov/pubmed/37034266
http://dx.doi.org/10.3389/fbioe.2023.1154272
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