Implantation of Embryonic Cardiomyocytes in a Post-Infarction Myocardium: A Long-Term Outcome after 25 Years of Follow-Up

In this article, we report the first case of embryonic cardiomyocyte implantation in a patient with severe ischemic heart lesions. In 1998, a 58-year-old male underwent coronary artery bypass grafting supplemented by injection of a pre-prepared suspension of human embryonic cardiomyocytes. During th...

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Autores principales: Schevchenko, Yu L, Gudymovich, VG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078966/
https://www.ncbi.nlm.nih.gov/pubmed/37034269
http://dx.doi.org/10.26502/acmcr.96550583
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author Schevchenko, Yu L
Gudymovich, VG
author_facet Schevchenko, Yu L
Gudymovich, VG
author_sort Schevchenko, Yu L
collection PubMed
description In this article, we report the first case of embryonic cardiomyocyte implantation in a patient with severe ischemic heart lesions. In 1998, a 58-year-old male underwent coronary artery bypass grafting supplemented by injection of a pre-prepared suspension of human embryonic cardiomyocytes. During the next 24 years, the patient felt well and reported quite satisfactory quality of life. He is currently 82 years old and also feels well. He has no signs of circulatory insufficiency. No complications associated with cell implantation were observed during the entire follow-up period.
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spelling pubmed-100789662023-04-06 Implantation of Embryonic Cardiomyocytes in a Post-Infarction Myocardium: A Long-Term Outcome after 25 Years of Follow-Up Schevchenko, Yu L Gudymovich, VG Arch Clin Med Case Rep Article In this article, we report the first case of embryonic cardiomyocyte implantation in a patient with severe ischemic heart lesions. In 1998, a 58-year-old male underwent coronary artery bypass grafting supplemented by injection of a pre-prepared suspension of human embryonic cardiomyocytes. During the next 24 years, the patient felt well and reported quite satisfactory quality of life. He is currently 82 years old and also feels well. He has no signs of circulatory insufficiency. No complications associated with cell implantation were observed during the entire follow-up period. 2023 2023-03-09 /pmc/articles/PMC10078966/ /pubmed/37034269 http://dx.doi.org/10.26502/acmcr.96550583 Text en https://creativecommons.org/licenses/by/4.0/This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license 4.0 (https://creativecommons.org/licenses/by/4.0/)
spellingShingle Article
Schevchenko, Yu L
Gudymovich, VG
Implantation of Embryonic Cardiomyocytes in a Post-Infarction Myocardium: A Long-Term Outcome after 25 Years of Follow-Up
title Implantation of Embryonic Cardiomyocytes in a Post-Infarction Myocardium: A Long-Term Outcome after 25 Years of Follow-Up
title_full Implantation of Embryonic Cardiomyocytes in a Post-Infarction Myocardium: A Long-Term Outcome after 25 Years of Follow-Up
title_fullStr Implantation of Embryonic Cardiomyocytes in a Post-Infarction Myocardium: A Long-Term Outcome after 25 Years of Follow-Up
title_full_unstemmed Implantation of Embryonic Cardiomyocytes in a Post-Infarction Myocardium: A Long-Term Outcome after 25 Years of Follow-Up
title_short Implantation of Embryonic Cardiomyocytes in a Post-Infarction Myocardium: A Long-Term Outcome after 25 Years of Follow-Up
title_sort implantation of embryonic cardiomyocytes in a post-infarction myocardium: a long-term outcome after 25 years of follow-up
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10078966/
https://www.ncbi.nlm.nih.gov/pubmed/37034269
http://dx.doi.org/10.26502/acmcr.96550583
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