Issues with RNF43 antibodies to reliably detect intracellular location

RNF43 is an important negative regulator of β-catenin signaling by removing Wnt-receptors from the membrane. It is often mutated in cancers, leading to aberrant Wnt-dependent nuclear translocation of β-catenin. RNF43 has also been suggested to regulate β-catenin signaling directly within the nucleus...

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Detalles Bibliográficos
Autores principales: Li, Shanshan, Zhang, Ruyi, Lavrijsen, Marla, van den Bosch, Thierry P. P., Peppelenbosch, Maikel P., Smits, Ron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079101/
https://www.ncbi.nlm.nih.gov/pubmed/37023034
http://dx.doi.org/10.1371/journal.pone.0283894

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079101/
https://www.ncbi.nlm.nih.gov/pubmed/37023034
http://dx.doi.org/10.1371/journal.pone.0283894

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