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Gerstmann Syndrome as a Disconnection Syndrome: A Single Case Diffusion Tensor Imaging Study
Gerstmann syndrome (GS) is a rare syndrome that occurs when there is a lesion of the dominant inferior parietal lobule (IPL), causing agraphia, acalculia, finger agnosia, and right-left disorientation. A 49-year-old right-handed male was diagnosed as GS after left parieto-occipital lobe hemorrhage....
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Neurorehabilitation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079479/ https://www.ncbi.nlm.nih.gov/pubmed/37033002 http://dx.doi.org/10.12786/bn.2023.16.e3 |
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author | Yoon, Soo Hoon Lee, Jae Ik Kang, Mun Jeong Lee, Hae In Pyun, Sung-Bom |
author_facet | Yoon, Soo Hoon Lee, Jae Ik Kang, Mun Jeong Lee, Hae In Pyun, Sung-Bom |
author_sort | Yoon, Soo Hoon |
collection | PubMed |
description | Gerstmann syndrome (GS) is a rare syndrome that occurs when there is a lesion of the dominant inferior parietal lobule (IPL), causing agraphia, acalculia, finger agnosia, and right-left disorientation. A 49-year-old right-handed male was diagnosed as GS after left parieto-occipital lobe hemorrhage. The patient showed mild anomic aphasia with agraphia in the language test and the neuropsychological test revealed acalculia, impaired right-left discrimination, and finger agnosia. In diffusion tensor tractography, the tracts of left superior longitudinal fasciculus (SLF), middle longitudinal fasciculus, U-fibers and posterior corpus callosum (CC) were disrupted around the left IPL. In addition, fractional anisotropy (FA) values were markedly decreased in left SLF, and posterior CC when compared to twelve healthy control subjects. Our clinical and neuroimaging findings support that GS is a disconnection syndrome caused by lesion in the white matter pathway surrounding IPL. In future, more studies of the correlation between the white matter disconnection and the development of GS including high quality imaging technique are needed. |
format | Online Article Text |
id | pubmed-10079479 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Korean Society for Neurorehabilitation |
record_format | MEDLINE/PubMed |
spelling | pubmed-100794792023-04-08 Gerstmann Syndrome as a Disconnection Syndrome: A Single Case Diffusion Tensor Imaging Study Yoon, Soo Hoon Lee, Jae Ik Kang, Mun Jeong Lee, Hae In Pyun, Sung-Bom Brain Neurorehabil Case Report Gerstmann syndrome (GS) is a rare syndrome that occurs when there is a lesion of the dominant inferior parietal lobule (IPL), causing agraphia, acalculia, finger agnosia, and right-left disorientation. A 49-year-old right-handed male was diagnosed as GS after left parieto-occipital lobe hemorrhage. The patient showed mild anomic aphasia with agraphia in the language test and the neuropsychological test revealed acalculia, impaired right-left discrimination, and finger agnosia. In diffusion tensor tractography, the tracts of left superior longitudinal fasciculus (SLF), middle longitudinal fasciculus, U-fibers and posterior corpus callosum (CC) were disrupted around the left IPL. In addition, fractional anisotropy (FA) values were markedly decreased in left SLF, and posterior CC when compared to twelve healthy control subjects. Our clinical and neuroimaging findings support that GS is a disconnection syndrome caused by lesion in the white matter pathway surrounding IPL. In future, more studies of the correlation between the white matter disconnection and the development of GS including high quality imaging technique are needed. Korean Society for Neurorehabilitation 2023-03-14 /pmc/articles/PMC10079479/ /pubmed/37033002 http://dx.doi.org/10.12786/bn.2023.16.e3 Text en Copyright © 2023. Korean Society for Neurorehabilitation https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Yoon, Soo Hoon Lee, Jae Ik Kang, Mun Jeong Lee, Hae In Pyun, Sung-Bom Gerstmann Syndrome as a Disconnection Syndrome: A Single Case Diffusion Tensor Imaging Study |
title | Gerstmann Syndrome as a Disconnection Syndrome: A Single Case Diffusion Tensor Imaging Study |
title_full | Gerstmann Syndrome as a Disconnection Syndrome: A Single Case Diffusion Tensor Imaging Study |
title_fullStr | Gerstmann Syndrome as a Disconnection Syndrome: A Single Case Diffusion Tensor Imaging Study |
title_full_unstemmed | Gerstmann Syndrome as a Disconnection Syndrome: A Single Case Diffusion Tensor Imaging Study |
title_short | Gerstmann Syndrome as a Disconnection Syndrome: A Single Case Diffusion Tensor Imaging Study |
title_sort | gerstmann syndrome as a disconnection syndrome: a single case diffusion tensor imaging study |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079479/ https://www.ncbi.nlm.nih.gov/pubmed/37033002 http://dx.doi.org/10.12786/bn.2023.16.e3 |
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