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QSAR and molecular docking studies of isatin and indole derivatives as SARS 3CL(pro) inhibitors

The 3C-like protease (3CL(pro)), known as the main protease of SARS-COV, plays a vital role in the viral replication cycle and is a critical target for the development of SARS inhibitor. Comparative sequence analysis has shown that the 3CL(pro) of two coronaviruses, SARS-CoV-2 and SARS-CoV, show hig...

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Detalles Bibliográficos
Autores principales:	Soleymani, Niousha, Ahmadi, Shahin, Shiri, Fereshteh, Almasirad, Ali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079496/ https://www.ncbi.nlm.nih.gov/pubmed/37024955 http://dx.doi.org/10.1186/s13065-023-00947-w

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