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Ras protein abundance correlates with Ras isoform mutation patterns in cancer

Activating mutations of Ras genes are often observed in cancer. The protein products of the three Ras genes are almost identical. However, for reasons that remain unclear, KRAS is far more frequently mutated than the other Ras isoforms in cancer and RASopathies. We have quantified HRAS, NRAS, KRAS4A...

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Detalles Bibliográficos
Autores principales:	Hood, Fiona E., Sahraoui, Yasmina M., Jenkins, Rosalind E., Prior, Ian A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079525/ https://www.ncbi.nlm.nih.gov/pubmed/36864243 http://dx.doi.org/10.1038/s41388-023-02638-1

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