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Nanoparticle-mediated targeting of the fusion gene RUNX1/ETO in t(8;21)-positive acute myeloid leukaemia

A hallmark of acute myeloid leukaemias (AMLs) are chromosomal rearrangements that give rise to novel leukaemia-specific fusion genes. Most of these fusion genes are both initiating and driving events in AML and therefore constitute ideal therapeutic targets but are challenging to target by conventio...

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Detalles Bibliográficos
Autores principales:	Issa, Hasan, Swart, Laura E., Rasouli, Milad, Ashtiani, Minoo, Nakjang, Sirintra, Jyotsana, Nidhi, Schuschel, Konstantin, Heuser, Michael, Blair, Helen, Heidenreich, Olaf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079536/ https://www.ncbi.nlm.nih.gov/pubmed/36823395 http://dx.doi.org/10.1038/s41375-023-01854-8

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