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Social disadvantage during pregnancy: effects on gestational age and birthweight

OBJECTIVE: Whether psychosocial adversity during pregnancy impacts fetal health outcomes at birth remains underexplored. This is a critical issue given significant social disadvantage and psychosocial stress faced by pregnant women worldwide. STUDY DESIGN: Measures of social disadvantage and psychol...

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Autores principales: Luby, Joan L., England, Sarah K., Barch, Deanna M., Warner, Barbara B., Rogers, Cynthia, Smyser, Christopher D., Triplett, Regina, Arora, Jyoti, Smyser, Tara A., Slavich, George M., Zhao, Peinan, Stout, Molly, Herzog, Erik, Miller, J. Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079545/
https://www.ncbi.nlm.nih.gov/pubmed/36914799
http://dx.doi.org/10.1038/s41372-023-01643-2
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author Luby, Joan L.
England, Sarah K.
Barch, Deanna M.
Warner, Barbara B.
Rogers, Cynthia
Smyser, Christopher D.
Triplett, Regina
Arora, Jyoti
Smyser, Tara A.
Slavich, George M.
Zhao, Peinan
Stout, Molly
Herzog, Erik
Miller, J. Philip
author_facet Luby, Joan L.
England, Sarah K.
Barch, Deanna M.
Warner, Barbara B.
Rogers, Cynthia
Smyser, Christopher D.
Triplett, Regina
Arora, Jyoti
Smyser, Tara A.
Slavich, George M.
Zhao, Peinan
Stout, Molly
Herzog, Erik
Miller, J. Philip
author_sort Luby, Joan L.
collection PubMed
description OBJECTIVE: Whether psychosocial adversity during pregnancy impacts fetal health outcomes at birth remains underexplored. This is a critical issue given significant social disadvantage and psychosocial stress faced by pregnant women worldwide. STUDY DESIGN: Measures of social disadvantage and psychological factors, and medical/reproductive and nutritional health status in pregnant women were obtained at each trimester. Using Structural Equation Modeling (SEM), we investigated the relationship of forms of adversity to each other and to infant gestational age, and birthweight. RESULTS: Among 399 singletons, Social Disadvantage significantly predicted gestational age (p = 0.003), and residual birthweight (p = 0.006). There was a 0.4 week decrease in gestational age and a 3% decrease in birthweight for each standard deviation increase in Social Disadvantage. CONCLUSION: Significant negative effects of social adversity on the developing fetus were found. Notably, these effects emerged despite good prenatal care and after accounting for maternal age and medical reproductive risk factors.
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spelling pubmed-100795452023-04-08 Social disadvantage during pregnancy: effects on gestational age and birthweight Luby, Joan L. England, Sarah K. Barch, Deanna M. Warner, Barbara B. Rogers, Cynthia Smyser, Christopher D. Triplett, Regina Arora, Jyoti Smyser, Tara A. Slavich, George M. Zhao, Peinan Stout, Molly Herzog, Erik Miller, J. Philip J Perinatol Article OBJECTIVE: Whether psychosocial adversity during pregnancy impacts fetal health outcomes at birth remains underexplored. This is a critical issue given significant social disadvantage and psychosocial stress faced by pregnant women worldwide. STUDY DESIGN: Measures of social disadvantage and psychological factors, and medical/reproductive and nutritional health status in pregnant women were obtained at each trimester. Using Structural Equation Modeling (SEM), we investigated the relationship of forms of adversity to each other and to infant gestational age, and birthweight. RESULTS: Among 399 singletons, Social Disadvantage significantly predicted gestational age (p = 0.003), and residual birthweight (p = 0.006). There was a 0.4 week decrease in gestational age and a 3% decrease in birthweight for each standard deviation increase in Social Disadvantage. CONCLUSION: Significant negative effects of social adversity on the developing fetus were found. Notably, these effects emerged despite good prenatal care and after accounting for maternal age and medical reproductive risk factors. Nature Publishing Group US 2023-03-13 2023 /pmc/articles/PMC10079545/ /pubmed/36914799 http://dx.doi.org/10.1038/s41372-023-01643-2 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Luby, Joan L.
England, Sarah K.
Barch, Deanna M.
Warner, Barbara B.
Rogers, Cynthia
Smyser, Christopher D.
Triplett, Regina
Arora, Jyoti
Smyser, Tara A.
Slavich, George M.
Zhao, Peinan
Stout, Molly
Herzog, Erik
Miller, J. Philip
Social disadvantage during pregnancy: effects on gestational age and birthweight
title Social disadvantage during pregnancy: effects on gestational age and birthweight
title_full Social disadvantage during pregnancy: effects on gestational age and birthweight
title_fullStr Social disadvantage during pregnancy: effects on gestational age and birthweight
title_full_unstemmed Social disadvantage during pregnancy: effects on gestational age and birthweight
title_short Social disadvantage during pregnancy: effects on gestational age and birthweight
title_sort social disadvantage during pregnancy: effects on gestational age and birthweight
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079545/
https://www.ncbi.nlm.nih.gov/pubmed/36914799
http://dx.doi.org/10.1038/s41372-023-01643-2
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