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Tryptase β regulation of joint lubrication and inflammation via proteoglycan-4 in osteoarthritis

PRG4 is an extracellular matrix protein that maintains homeostasis through its boundary lubricating and anti-inflammatory properties. Altered expression and function of PRG4 have been associated with joint inflammatory diseases, including osteoarthritis. Here we show that mast cell tryptase β cleave...

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Detalles Bibliográficos
Autores principales:	Das, Nabangshu, de Almeida, Luiz G. N., Derakhshani, Afshin, Young, Daniel, Mehdinejadiani, Kobra, Salo, Paul, Rezansoff, Alexander, Jay, Gregory D., Sommerhoff, Christian P., Schmidt, Tannin A., Krawetz, Roman, Dufour, Antoine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079686/ https://www.ncbi.nlm.nih.gov/pubmed/37024468 http://dx.doi.org/10.1038/s41467-023-37598-3

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