Cargando…

The chaperone system in cancer therapies: Hsp90

The chaperone system (CS) of an organism is composed of molecular chaperones, chaperone co-factors, co-chaperones, and chaperone receptors and interactors. It is present throughout the body but with distinctive features for each cell and tissue type. Previous studies pertaining to the CS of the sali...

Descripción completa

Detalles Bibliográficos
Autores principales:	Basset, Charbel A., Conway de Macario, Everly, Leone, Lavinia Giovanna, Macario, Alberto J.L., Leone, Angelo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2023
Materias:	Review Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079721/ https://www.ncbi.nlm.nih.gov/pubmed/36933095 http://dx.doi.org/10.1007/s10735-023-10119-8

Ejemplares similares

The Chaperone System in Salivary Glands: Hsp90 Prospects for Differential Diagnosis and Treatment of Malignant Tumors
por: Basset, Charbel A., et al.
Publicado: (2022)

The Chaperone System in Breast Cancer: Roles and Therapeutic Prospects of the Molecular Chaperones Hsp27, Hsp60, Hsp70, and Hsp90
por: Alberti, Giusi, et al.
Publicado: (2022)

hsp70 genes in the human genome: Conservation and differentiation patterns predict a wide array of overlapping and specialized functions
por: Brocchieri, Luciano, et al.
Publicado: (2008)

Editorial: Pathologic Conditions of the Human Nervous and Muscular Systems Associated with Mutant Chaperones: Molecular and Mechanistic Aspects
por: Macario, Alberto J. L., et al.
Publicado: (2018)

HSP60 activity on human bronchial epithelial cells
por: Sangiorgi, Claudia, et al.
Publicado: (2017)

Myelin Pathology: Involvement of Molecular Chaperones and the Promise of Chaperonotherapy
por: Scalia, Federica, et al.
Publicado: (2019)

The Role of Molecular Chaperones in Virus Infection and Implications for Understanding and Treating COVID-19
por: Paladino, Letizia, et al.
Publicado: (2020)

SARS-CoV-2 in patients with cancer: possible role of mimicry of human molecules by viral proteins and the resulting anti-cancer immunity
por: Burgio, Stefano, et al.
Publicado: (2021)

Hsp60 as a Novel Target in IBD Management: A Prospect
por: Cappello, Francesco, et al.
Publicado: (2019)

Molecular Chaperones and Thyroid Cancer
por: Paladino, Letizia, et al.
Publicado: (2021)

Chlamydia trachomatis Infection and Anti-Hsp60 Immunity: The Two Sides of the Coin
por: Cappello, Francesco, et al.
Publicado: (2009)

Role of Molecular Chaperones in Carcinogenesis: Mechanism, Diagnosis, and Treatment
por: Conway de Macario, Everly, et al.
Publicado: (2020)

Chaperonin genes on the rise: new divergent classes and intense duplication in human and other vertebrate genomes
por: Mukherjee, Krishanu, et al.
Publicado: (2010)

Human molecular chaperones share with SARS-CoV-2 antigenic epitopes potentially capable of eliciting autoimmunity against endothelial cells: possible role of molecular mimicry in COVID-19
por: Marino Gammazza, Antonella, et al.
Publicado: (2020)

Circulating Molecular Chaperones in Subjects with Amnestic Mild Cognitive Impairment and Alzheimer’s Disease: Data from the Zabùt Aging Project
por: Marino Gammazza, Antonella, et al.
Publicado: (2022)

Missense Mutations of Human Hsp60: A Computational Analysis to Unveil Their Pathological Significance
por: Vitale, Alessandra Maria, et al.
Publicado: (2020)

Hsp10, Hsp70, and Hsp90 immunohistochemical levels change in ulcerative colitis after therapy
por: Tomasello, G., et al.
Publicado: (2011)

Does SARS-CoV-2 Trigger Stress-Induced Autoimmunity by Molecular Mimicry? A Hypothesis
por: Cappello, Francesco, et al.
Publicado: (2020)

The histone deacetylase inhibitor SAHA induces HSP60 nitration and its extracellular release by exosomal vesicles in human lung-derived carcinoma cells
por: Campanella, Claudia, et al.
Publicado: (2015)

Prokaryotic Chaperonins as Experimental Models for Elucidating Structure-Function Abnormalities of Human Pathogenic Mutant Counterparts
por: Conway de Macario, Everly, et al.
Publicado: (2017)

Immunomorphological Patterns of Chaperone System Components in Rare Thyroid Tumors with Promise as Biomarkers for Differential Diagnosis and Providing Clues on Molecular Mechanisms of Carcinogenesis
por: Paladino, Letizia, et al.
Publicado: (2023)

Molecular mimicry may explain multi-organ damage in COVID-19
por: Angileri, Francesca, et al.
Publicado: (2020)

Unexpected tumor reduction in metastatic colorectal cancer patients during SARS-Cov-2 infection: effect of ACE-2 expression on tumor cells or molecular mimicry phenomena? Two not mutually exclusive hypotheses
por: Cappello, Francesco, et al.
Publicado: (2021)

Salivary gland proteins alterations in the diabetic milieu
por: Fouani, Malak, et al.
Publicado: (2021)

Histopathology of Skeletal Muscle in a Distal Motor Neuropathy Associated with a Mutant CCT5 Subunit: Clues for Future Developments to Improve Differential Diagnosis and Personalized Therapy
por: Scalia, Federica, et al.
Publicado: (2023)

Alterations of the Hsp70/Hsp90 chaperone and the HOP/CHIP co-chaperone system in cancer
por: Ruckova, Eva, et al.
Publicado: (2012)

Hsp60 Post-translational Modifications: Functional and Pathological Consequences
por: Caruso Bavisotto, Celeste, et al.
Publicado: (2020)

Lipid chaperones and associated diseases: a group of chaperonopathies defining a new nosological entity with implications for medical research and practice
por: D’Anneo, Antonella, et al.
Publicado: (2020)

MATURATION OF THE IMMUNE RESPONSE IN VITRO : FOCAL FLUCTUATION AND CHANGES IN AFFINITY OF ANTI-β-D-GALACTOSIDASE ACTIVATING ANTIBODY
por: Macario, Alberto J. L., et al.
Publicado: (1972)

Bridging human chaperonopathies and microbial chaperonins
por: Conway de Macario, Everly, et al.
Publicado: (2019)

Hsp60 Is Actively Secreted by Human Tumor Cells
por: Merendino, Anna M., et al.
Publicado: (2010)

Hsp110 Chaperones Control Client Fate Determination in the Hsp70–Hsp90 Chaperone System
por: Mandal, Atin K., et al.
Publicado: (2010)

Exosomal Chaperones and miRNAs in Gliomagenesis: State-of-Art and Theranostics Perspectives
por: Caruso Bavisotto, Celeste, et al.
Publicado: (2018)

Molecular Chaperones and miRNAs in Epilepsy: Pathogenic Implications and Therapeutic Prospects
por: Zummo, Leila, et al.
Publicado: (2021)

The Odyssey of Hsp60 from Tumor Cells to Other Destinations Includes Plasma Membrane-Associated Stages and Golgi and Exosomal Protein-Trafficking Modalities
por: Campanella, Claudia, et al.
Publicado: (2012)

NF-kB Regulation and the Chaperone System Mediate Restorative Effects of the Probiotic Lactobacillus fermentum LF31 in the Small Intestine and Cerebellum of Mice with Ethanol-Induced Damage
por: Paladino, Letizia, et al.
Publicado: (2023)

Natural Iminosugar (+)-Lentiginosine Inhibits ATPase and Chaperone Activity of Hsp90
por: Dal Piaz, Fabrizio, et al.
Publicado: (2012)

The Hsp70/Hsp90 Chaperone Machinery in Neurodegenerative Diseases
por: Lackie, Rachel E., et al.
Publicado: (2017)

Constitutively-active androgen receptor variants function independently of the HSP90 chaperone but do not confer resistance to HSP90 inhibitors
por: Gillis, Joanna L., et al.
Publicado: (2013)

Hsp60 response in experimental and human temporal lobe epilepsy
por: Gammazza, Antonella Marino, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_ift0gmk20atv8tdtcpb54od5ug