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PRMT3-mediated arginine methylation of IGF2BP1 promotes oxaliplatin resistance in liver cancer

Although oxaliplatin-based chemotherapy has been effective in the treatment of hepatocellular carcinoma (HCC), primary or acquired resistance to oxaliplatin remains a major challenge in the clinic. Through functional screening using CRISPR/Cas9 activation library, transcriptomic profiling of clinica...

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Detalles Bibliográficos
Autores principales:	Shi, Yunxing, Niu, Yi, Yuan, Yichuan, Li, Kai, Zhong, Chengrui, Qiu, Zhiyu, Li, Keren, Lin, Zhu, Yang, Zhiwen, Zuo, Dinglan, Qiu, Jiliang, He, Wei, Wang, Chenwei, Liao, Yadi, Wang, Guocan, Yuan, Yunfei, Li, Binkui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079833/ https://www.ncbi.nlm.nih.gov/pubmed/37024475 http://dx.doi.org/10.1038/s41467-023-37542-5

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