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Drug-induced loss of imprinting revealed using bioluminescent reporters of Cdkn1c

Genomic imprinting is an epigenetically mediated mechanism that regulates allelic expression of genes based upon parent-of-origin and provides a paradigm for studying epigenetic silencing and release. Here, bioluminescent reporters for the maternally-expressed imprinted gene Cdkn1c are used to exami...

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Detalles Bibliográficos
Autores principales:	Dimond, Andrew, Van de Pette, Mathew, Taylor-Bateman, Victoria, Brown, Karen, Sardini, Alessandro, Whilding, Chad, Feytout, Amelie, Prinjha, Rab K., Merkenschlager, Matthias, Fisher, Amanda G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079848/ https://www.ncbi.nlm.nih.gov/pubmed/37024615 http://dx.doi.org/10.1038/s41598-023-32747-6

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