Case report: Ultrasound-guided percutaneous drainage combined with lavage using urokinase: An economical and effective treatment for muscular hematomas in hemophiliacs

This was an initial effort to treat hemophiliac hematoma by ultrasound-guided intratumoral drainage and lavage with urokinase after adequate supplementation of coagulation factors. Two patients with severe hemophilia underwent ultrasound-guided percutaneous drainage in combination with lavage using...

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Autores principales: Liu, Hao, Xu, Cong, Wang, Weizhen, Chen, Bin, Sun, Jing, Feng, Xiaoqin, Zhang, Yaru, Ma, Fei, Du, Lingli, Gao, Yang, Li, Yingjia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Surgery
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079870/
https://www.ncbi.nlm.nih.gov/pubmed/37035572
http://dx.doi.org/10.3389/fsurg.2023.1023329
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author Liu, Hao
Xu, Cong
Wang, Weizhen
Chen, Bin
Sun, Jing
Feng, Xiaoqin
Zhang, Yaru
Ma, Fei
Du, Lingli
Gao, Yang
Li, Yingjia
author_facet Liu, Hao
Xu, Cong
Wang, Weizhen
Chen, Bin
Sun, Jing
Feng, Xiaoqin
Zhang, Yaru
Ma, Fei
Du, Lingli
Gao, Yang
Li, Yingjia
author_sort Liu, Hao
collection PubMed
description This was an initial effort to treat hemophiliac hematoma by ultrasound-guided intratumoral drainage and lavage with urokinase after adequate supplementation of coagulation factors. Two patients with severe hemophilia underwent ultrasound-guided percutaneous drainage in combination with lavage using urokinase. After 5-day and 3-day treatments, respectively, intramuscular hematomas in both patients disappeared, compression symptom was relieved, and no obvious adverse reactions or serious complications were observed during the treatment or follow-up. These findings suggest that ultrasound-guided drainage combined with lavage using urokinase is an immediate, safe, effective, and minimally invasive treatment for intramuscular hematomas in hemophiliacs, avoiding potential complications by surgical resection with relatively low treatment cost.
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spelling pubmed-100798702023-04-08 Case report: Ultrasound-guided percutaneous drainage combined with lavage using urokinase: An economical and effective treatment for muscular hematomas in hemophiliacs Liu, Hao Xu, Cong Wang, Weizhen Chen, Bin Sun, Jing Feng, Xiaoqin Zhang, Yaru Ma, Fei Du, Lingli Gao, Yang Li, Yingjia Front Surg Surgery This was an initial effort to treat hemophiliac hematoma by ultrasound-guided intratumoral drainage and lavage with urokinase after adequate supplementation of coagulation factors. Two patients with severe hemophilia underwent ultrasound-guided percutaneous drainage in combination with lavage using urokinase. After 5-day and 3-day treatments, respectively, intramuscular hematomas in both patients disappeared, compression symptom was relieved, and no obvious adverse reactions or serious complications were observed during the treatment or follow-up. These findings suggest that ultrasound-guided drainage combined with lavage using urokinase is an immediate, safe, effective, and minimally invasive treatment for intramuscular hematomas in hemophiliacs, avoiding potential complications by surgical resection with relatively low treatment cost. Frontiers Media S.A. 2023-03-24 /pmc/articles/PMC10079870/ /pubmed/37035572 http://dx.doi.org/10.3389/fsurg.2023.1023329 Text en © 2023 Liu, Xu, Wang, Chen, Sun, Feng, Zhang, Ma, Du, Gao and Li. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Surgery
Liu, Hao
Xu, Cong
Wang, Weizhen
Chen, Bin
Sun, Jing
Feng, Xiaoqin
Zhang, Yaru
Ma, Fei
Du, Lingli
Gao, Yang
Li, Yingjia
Case report: Ultrasound-guided percutaneous drainage combined with lavage using urokinase: An economical and effective treatment for muscular hematomas in hemophiliacs
title Case report: Ultrasound-guided percutaneous drainage combined with lavage using urokinase: An economical and effective treatment for muscular hematomas in hemophiliacs
title_full Case report: Ultrasound-guided percutaneous drainage combined with lavage using urokinase: An economical and effective treatment for muscular hematomas in hemophiliacs
title_fullStr Case report: Ultrasound-guided percutaneous drainage combined with lavage using urokinase: An economical and effective treatment for muscular hematomas in hemophiliacs
title_full_unstemmed Case report: Ultrasound-guided percutaneous drainage combined with lavage using urokinase: An economical and effective treatment for muscular hematomas in hemophiliacs
title_short Case report: Ultrasound-guided percutaneous drainage combined with lavage using urokinase: An economical and effective treatment for muscular hematomas in hemophiliacs
title_sort case report: ultrasound-guided percutaneous drainage combined with lavage using urokinase: an economical and effective treatment for muscular hematomas in hemophiliacs
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079870/
https://www.ncbi.nlm.nih.gov/pubmed/37035572
http://dx.doi.org/10.3389/fsurg.2023.1023329
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