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Integrated bioinformatic analysis and cell line experiments reveal the significant role of the novel immune checkpoint TIGIT in kidney renal clear cell carcinoma

BACKGROUND: T cell immunoglobulin and ITIM domain (TIGIT) is a widely concerned immune checkpoint, which plays an essential role in immunosuppression and immune evasion. However, the role of TIGIT in normal organ tissues and renal clear cell carcinoma is unclear. We aim to identify the critical role...

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Detalles Bibliográficos
Autores principales:	Xia, Qi-Dong, Li, Bo, Sun, Jian-Xuan, Liu, Chen-Qian, Xu, Jin-Zhou, An, Ye, Xu, Meng-Yao, Zhang, Si-Han, Zhong, Xing-Yu, Zeng, Na, Ma, Si-Yang, He, Hao-Dong, Zhang, Yu-Cong, Guan, Wei, Li, Heng, Wang, Shao-Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079921/ https://www.ncbi.nlm.nih.gov/pubmed/37035135 http://dx.doi.org/10.3389/fonc.2023.1096341

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