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Neurointerface with oscillator motifs for inhibitory effect over antagonist muscles
The effect of inhibitory management is usually underestimated in artificial control systems, using biological analogy. According to our hypothesis, the muscle hypertonus could be effectively compensated via stimulation by bio-plausible patterns. We proposed an approach for the compensatory stimulati...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079922/ https://www.ncbi.nlm.nih.gov/pubmed/37034155 http://dx.doi.org/10.3389/fnins.2023.1113867 |
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author | Mikhailova, Yulia Pozdeeva, Anna Suleimanova, Alina Leukhin, Alexey Toschev, Alexander Lukmanov, Timur Fatyhova, Elsa Magid, Evgeni Lavrov, Igor Talanov, Max |
author_facet | Mikhailova, Yulia Pozdeeva, Anna Suleimanova, Alina Leukhin, Alexey Toschev, Alexander Lukmanov, Timur Fatyhova, Elsa Magid, Evgeni Lavrov, Igor Talanov, Max |
author_sort | Mikhailova, Yulia |
collection | PubMed |
description | The effect of inhibitory management is usually underestimated in artificial control systems, using biological analogy. According to our hypothesis, the muscle hypertonus could be effectively compensated via stimulation by bio-plausible patterns. We proposed an approach for the compensatory stimulation device as implementation of previously presented architecture of the neurointerface, where (1) the neuroport is implemented as a DAC and stimulator, (2) neuroterminal is used for neurosimulation of a set of oscillator motifs on one-board computer. In the set of experiments with five volunteers, we measured the efficacy of motor neuron inhibition via the antagonist muscle or nerve stimulation registering muscle force with and without antagonist stimulation. For the agonist activation, we used both voluntary activity and electrical stimulation. In the case of stimulation of both the agonist and the antagonist muscles and nerves, we experimented with delays between muscle stimulation in the range of 0–20 ms. We registered the subjective discomfort rate. We did not identify any significant difference between the antagonist muscle and nerve stimulation in both voluntary activity and electrical stimulation of cases showing agonist activity. We determined the most effective delay between the stimulation of the agonist and the antagonist muscles and nerves as 10–20 ms. |
format | Online Article Text |
id | pubmed-10079922 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-100799222023-04-08 Neurointerface with oscillator motifs for inhibitory effect over antagonist muscles Mikhailova, Yulia Pozdeeva, Anna Suleimanova, Alina Leukhin, Alexey Toschev, Alexander Lukmanov, Timur Fatyhova, Elsa Magid, Evgeni Lavrov, Igor Talanov, Max Front Neurosci Neuroscience The effect of inhibitory management is usually underestimated in artificial control systems, using biological analogy. According to our hypothesis, the muscle hypertonus could be effectively compensated via stimulation by bio-plausible patterns. We proposed an approach for the compensatory stimulation device as implementation of previously presented architecture of the neurointerface, where (1) the neuroport is implemented as a DAC and stimulator, (2) neuroterminal is used for neurosimulation of a set of oscillator motifs on one-board computer. In the set of experiments with five volunteers, we measured the efficacy of motor neuron inhibition via the antagonist muscle or nerve stimulation registering muscle force with and without antagonist stimulation. For the agonist activation, we used both voluntary activity and electrical stimulation. In the case of stimulation of both the agonist and the antagonist muscles and nerves, we experimented with delays between muscle stimulation in the range of 0–20 ms. We registered the subjective discomfort rate. We did not identify any significant difference between the antagonist muscle and nerve stimulation in both voluntary activity and electrical stimulation of cases showing agonist activity. We determined the most effective delay between the stimulation of the agonist and the antagonist muscles and nerves as 10–20 ms. Frontiers Media S.A. 2023-03-24 /pmc/articles/PMC10079922/ /pubmed/37034155 http://dx.doi.org/10.3389/fnins.2023.1113867 Text en Copyright © 2023 Mikhailova, Pozdeeva, Suleimanova, Leukhin, Toschev, Lukmanov, Fatyhova, Magid, Lavrov and Talanov. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neuroscience Mikhailova, Yulia Pozdeeva, Anna Suleimanova, Alina Leukhin, Alexey Toschev, Alexander Lukmanov, Timur Fatyhova, Elsa Magid, Evgeni Lavrov, Igor Talanov, Max Neurointerface with oscillator motifs for inhibitory effect over antagonist muscles |
title | Neurointerface with oscillator motifs for inhibitory effect over antagonist muscles |
title_full | Neurointerface with oscillator motifs for inhibitory effect over antagonist muscles |
title_fullStr | Neurointerface with oscillator motifs for inhibitory effect over antagonist muscles |
title_full_unstemmed | Neurointerface with oscillator motifs for inhibitory effect over antagonist muscles |
title_short | Neurointerface with oscillator motifs for inhibitory effect over antagonist muscles |
title_sort | neurointerface with oscillator motifs for inhibitory effect over antagonist muscles |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079922/ https://www.ncbi.nlm.nih.gov/pubmed/37034155 http://dx.doi.org/10.3389/fnins.2023.1113867 |
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