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Tat-malate dehydrogenase fusion protein protects neurons from oxidative and ischemic damage by reduction of reactive oxygen species and modulation of glutathione redox system

Malate dehydrogenase (MDH) plays an important role in the conversion of malate to oxaloacetate during the tricarboxylic acid cycle. In this study, we examined the role of cytoplasmic MDH (MDH1) in hydrogen peroxide (H(2)O(2))-induced oxidative stress in HT22 cells and ischemia-induced neuronal damag...

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Detalles Bibliográficos
Autores principales:	Kwon, Hyun Jung, Hahn, Kyu Ri, Kang, Min Soo, Choi, Jung Hoon, Moon, Seung Myung, Yoon, Yeo Sung, Hwang, In Koo, Kim, Dae Won
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079925/ https://www.ncbi.nlm.nih.gov/pubmed/37024665 http://dx.doi.org/10.1038/s41598-023-32812-0

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