Immunomodulatory therapy with glatiramer acetate reduces endoplasmic reticulum stress and mitochondrial dysfunction in experimental autoimmune encephalomyelitis

Endoplasmic reticulum (ER) stress and mitochondrial dysfunction are found in lesions of multiple sclerosis (MS) and animal models of MS such as experimental autoimmune encephalomyelitis (EAE), and may contribute to the neuronal loss that underlies permanent impairment. We investigated whether glatir...

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Detalles Bibliográficos
Autores principales: Makar, Tapas K., Guda, Poornachander R., Ray, Sugata, Andhavarapu, Sanketh, Keledjian, Kaspar, Gerzanich, Volodymyr, Simard, J. Marc, Nimmagadda, Vamshi K. C., Bever, Christopher T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079956/
https://www.ncbi.nlm.nih.gov/pubmed/37024509
http://dx.doi.org/10.1038/s41598-023-29852-x

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