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Nasopharyngeal carcinoma cells promote regulatory T cell development and suppressive activity via CD70-CD27 interaction

Despite the intense CD8+ T-cell infiltration in the tumor microenvironment of nasopharyngeal carcinoma, anti-PD-1 immunotherapy shows an unsatisfactory response rate in clinical trials, hindered by immunosuppressive signals. To understand how microenvironmental characteristics alter immune homeostas...

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Detalles Bibliográficos
Autores principales:	Gong, Lanqi, Luo, Jie, Zhang, Yu, Yang, Yuma, Li, Shanshan, Fang, Xiaona, Zhang, Baifeng, Huang, Jiao, Chow, Larry Ka-Yue, Chung, Dittman, Huang, Jinlin, Huang, Cuicui, Liu, Qin, Bai, Lu, Tiu, Yuen Chak, Wu, Pingan, Wang, Yan, Tsao, George Sai-Wah, Kwong, Dora Lai-wan, Lee, Anne Wing-Mui, Dai, Wei, Guan, Xin-Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079957/ https://www.ncbi.nlm.nih.gov/pubmed/37024479 http://dx.doi.org/10.1038/s41467-023-37614-6

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