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Automatic bundle-specific white matter fiber tracking tool using diffusion tensor imaging data: A pilot trial in the application of language-related glioma resection

Cerebral neoplasms like gliomas may cause intracranial pressure increasing, neural tract deviation, infiltration, or destruction in peritumoral areas, leading to neuro-functional deficits. Novel tracking technology, such as DTI, can objectively reveal and visualize three-dimensional white matter tra...

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Autores principales: Yuan, Yifan, Qiu, Tianming, Chong, Shin Tai, Hsu, Sanford Pin-Chuan, Chu, Ying-Hua, Hsu, Yi-Cheng, Xu, Geng, Ko, Yu-Ting, Kuo, Kuan-Tsen, Yang, Zixiao, Zhu, Wei, Lin, Ching-Po, Song, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080097/
https://www.ncbi.nlm.nih.gov/pubmed/37035157
http://dx.doi.org/10.3389/fonc.2023.1089923
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author Yuan, Yifan
Qiu, Tianming
Chong, Shin Tai
Hsu, Sanford Pin-Chuan
Chu, Ying-Hua
Hsu, Yi-Cheng
Xu, Geng
Ko, Yu-Ting
Kuo, Kuan-Tsen
Yang, Zixiao
Zhu, Wei
Lin, Ching-Po
Song, Jianping
author_facet Yuan, Yifan
Qiu, Tianming
Chong, Shin Tai
Hsu, Sanford Pin-Chuan
Chu, Ying-Hua
Hsu, Yi-Cheng
Xu, Geng
Ko, Yu-Ting
Kuo, Kuan-Tsen
Yang, Zixiao
Zhu, Wei
Lin, Ching-Po
Song, Jianping
author_sort Yuan, Yifan
collection PubMed
description Cerebral neoplasms like gliomas may cause intracranial pressure increasing, neural tract deviation, infiltration, or destruction in peritumoral areas, leading to neuro-functional deficits. Novel tracking technology, such as DTI, can objectively reveal and visualize three-dimensional white matter trajectories; in combination with intraoperative navigation, it can help achieve maximum resection whilst minimizing neurological deficit. Since the reconstruction of DTI raw data largely relies on the technical engineering and anatomical experience of the operator; it is time-consuming and prone to operator-induced bias. Here, we develop new user-friendly software to automatically segment and reconstruct functionally active areas to facilitate precise surgery. In this pilot trial, we used an in-house developed software (DiffusionGo) specially designed for neurosurgeons, which integrated a reliable diffusion-weighted image (DWI) preprocessing pipeline that embedded several functionalities from software packages of FSL, MRtrix3, and ANTs. The preprocessing pipeline is as follows: 1. DWI denoising, 2. Gibbs-ringing removing, 3. Susceptibility distortion correction (process if opposite polarity data were acquired), 4. Eddy current and motion correction, and 5. Bias correction. Then, this fully automatic multiple assigned criteria algorithms for fiber tracking were used to achieve easy modeling and assist precision surgery. We demonstrated the application with three language-related cases in three different centers, including a left frontal, a left temporal, and a left frontal-temporal glioma, to achieve a favorable surgical outcome with language function preservation or recovery. The DTI tracking result using DiffusionGo showed robust consistency with direct cortical stimulation (DCS) finding. We believe that this fully automatic processing pipeline provides the neurosurgeon with a solution that may reduce time costs and operating errors and improve care quality and surgical procedure quality across different neurosurgical centers.
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spelling pubmed-100800972023-04-08 Automatic bundle-specific white matter fiber tracking tool using diffusion tensor imaging data: A pilot trial in the application of language-related glioma resection Yuan, Yifan Qiu, Tianming Chong, Shin Tai Hsu, Sanford Pin-Chuan Chu, Ying-Hua Hsu, Yi-Cheng Xu, Geng Ko, Yu-Ting Kuo, Kuan-Tsen Yang, Zixiao Zhu, Wei Lin, Ching-Po Song, Jianping Front Oncol Oncology Cerebral neoplasms like gliomas may cause intracranial pressure increasing, neural tract deviation, infiltration, or destruction in peritumoral areas, leading to neuro-functional deficits. Novel tracking technology, such as DTI, can objectively reveal and visualize three-dimensional white matter trajectories; in combination with intraoperative navigation, it can help achieve maximum resection whilst minimizing neurological deficit. Since the reconstruction of DTI raw data largely relies on the technical engineering and anatomical experience of the operator; it is time-consuming and prone to operator-induced bias. Here, we develop new user-friendly software to automatically segment and reconstruct functionally active areas to facilitate precise surgery. In this pilot trial, we used an in-house developed software (DiffusionGo) specially designed for neurosurgeons, which integrated a reliable diffusion-weighted image (DWI) preprocessing pipeline that embedded several functionalities from software packages of FSL, MRtrix3, and ANTs. The preprocessing pipeline is as follows: 1. DWI denoising, 2. Gibbs-ringing removing, 3. Susceptibility distortion correction (process if opposite polarity data were acquired), 4. Eddy current and motion correction, and 5. Bias correction. Then, this fully automatic multiple assigned criteria algorithms for fiber tracking were used to achieve easy modeling and assist precision surgery. We demonstrated the application with three language-related cases in three different centers, including a left frontal, a left temporal, and a left frontal-temporal glioma, to achieve a favorable surgical outcome with language function preservation or recovery. The DTI tracking result using DiffusionGo showed robust consistency with direct cortical stimulation (DCS) finding. We believe that this fully automatic processing pipeline provides the neurosurgeon with a solution that may reduce time costs and operating errors and improve care quality and surgical procedure quality across different neurosurgical centers. Frontiers Media S.A. 2023-03-24 /pmc/articles/PMC10080097/ /pubmed/37035157 http://dx.doi.org/10.3389/fonc.2023.1089923 Text en Copyright © 2023 Yuan, Qiu, Chong, Hsu, Chu, Hsu, Xu, Ko, Kuo, Yang, Zhu, Lin and Song https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Yuan, Yifan
Qiu, Tianming
Chong, Shin Tai
Hsu, Sanford Pin-Chuan
Chu, Ying-Hua
Hsu, Yi-Cheng
Xu, Geng
Ko, Yu-Ting
Kuo, Kuan-Tsen
Yang, Zixiao
Zhu, Wei
Lin, Ching-Po
Song, Jianping
Automatic bundle-specific white matter fiber tracking tool using diffusion tensor imaging data: A pilot trial in the application of language-related glioma resection
title Automatic bundle-specific white matter fiber tracking tool using diffusion tensor imaging data: A pilot trial in the application of language-related glioma resection
title_full Automatic bundle-specific white matter fiber tracking tool using diffusion tensor imaging data: A pilot trial in the application of language-related glioma resection
title_fullStr Automatic bundle-specific white matter fiber tracking tool using diffusion tensor imaging data: A pilot trial in the application of language-related glioma resection
title_full_unstemmed Automatic bundle-specific white matter fiber tracking tool using diffusion tensor imaging data: A pilot trial in the application of language-related glioma resection
title_short Automatic bundle-specific white matter fiber tracking tool using diffusion tensor imaging data: A pilot trial in the application of language-related glioma resection
title_sort automatic bundle-specific white matter fiber tracking tool using diffusion tensor imaging data: a pilot trial in the application of language-related glioma resection
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080097/
https://www.ncbi.nlm.nih.gov/pubmed/37035157
http://dx.doi.org/10.3389/fonc.2023.1089923
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