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Lung ultrasound in children and adolescents with long-term effects of COVID-19: Initial results

INTRODUCTION: Chronic health effects following acute COVID-19 are increasingly observed as the pandemic continues and are grouped under long COVID. Although the acute course of the COVID disease is often milder, long COVID also affects children and adolescents. As the symptoms present in Long-COVID...

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Autores principales: Gräger, Stephanie, Pfirschke, Rosalie, Lorenz, Michael, Vilser, Daniel, Krämer, Martin, Mentzel, Hans-Joachim, Glutig, Katja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080098/
https://www.ncbi.nlm.nih.gov/pubmed/37033176
http://dx.doi.org/10.3389/fped.2023.1112881
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author Gräger, Stephanie
Pfirschke, Rosalie
Lorenz, Michael
Vilser, Daniel
Krämer, Martin
Mentzel, Hans-Joachim
Glutig, Katja
author_facet Gräger, Stephanie
Pfirschke, Rosalie
Lorenz, Michael
Vilser, Daniel
Krämer, Martin
Mentzel, Hans-Joachim
Glutig, Katja
author_sort Gräger, Stephanie
collection PubMed
description INTRODUCTION: Chronic health effects following acute COVID-19 are increasingly observed as the pandemic continues and are grouped under long COVID. Although the acute course of the COVID disease is often milder, long COVID also affects children and adolescents. As the symptoms present in Long-COVID often seem to be non-specific and not limited to organ systems, clarification of the causes and the creation of a meaningful, efficient and targeted diagnostic algorithm is urgently needed. METHODS: Therefore, in this prospective observational study, we examined 30 children with long COVID using lung ultrasound and compared the results with those of 15 lung-healthy children. RESULTS: In our study, no significant difference was found between the two groups in the morphological criteria of lung ultrasound of the pleura or pleural lung structures. There was no significant correlation between the lung ultrasound findings and clinical Data. DISCUSSION: Our findings are congruent with the current, albeit sparse, data. It is possible that the causes of persistent thoracic symptoms in long COVID might be more likely to be present in functional examinations, but not morphologically imageable. Nonspecific symptoms do not appear to be due to changes in the lung parenchyma. In conclusion, lung ultrasound alone and without baseline in acute disease is not suitable as a standard in the follow-up of long COVID patients. Further investigations on the morphological and functional changes in patient with long COVID is needed.
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spelling pubmed-100800982023-04-08 Lung ultrasound in children and adolescents with long-term effects of COVID-19: Initial results Gräger, Stephanie Pfirschke, Rosalie Lorenz, Michael Vilser, Daniel Krämer, Martin Mentzel, Hans-Joachim Glutig, Katja Front Pediatr Pediatrics INTRODUCTION: Chronic health effects following acute COVID-19 are increasingly observed as the pandemic continues and are grouped under long COVID. Although the acute course of the COVID disease is often milder, long COVID also affects children and adolescents. As the symptoms present in Long-COVID often seem to be non-specific and not limited to organ systems, clarification of the causes and the creation of a meaningful, efficient and targeted diagnostic algorithm is urgently needed. METHODS: Therefore, in this prospective observational study, we examined 30 children with long COVID using lung ultrasound and compared the results with those of 15 lung-healthy children. RESULTS: In our study, no significant difference was found between the two groups in the morphological criteria of lung ultrasound of the pleura or pleural lung structures. There was no significant correlation between the lung ultrasound findings and clinical Data. DISCUSSION: Our findings are congruent with the current, albeit sparse, data. It is possible that the causes of persistent thoracic symptoms in long COVID might be more likely to be present in functional examinations, but not morphologically imageable. Nonspecific symptoms do not appear to be due to changes in the lung parenchyma. In conclusion, lung ultrasound alone and without baseline in acute disease is not suitable as a standard in the follow-up of long COVID patients. Further investigations on the morphological and functional changes in patient with long COVID is needed. Frontiers Media S.A. 2023-03-24 /pmc/articles/PMC10080098/ /pubmed/37033176 http://dx.doi.org/10.3389/fped.2023.1112881 Text en © 2023 Gräger, Pfirschke, Lorenz, Vilser, Krämer, Mentzel and Glutig. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Gräger, Stephanie
Pfirschke, Rosalie
Lorenz, Michael
Vilser, Daniel
Krämer, Martin
Mentzel, Hans-Joachim
Glutig, Katja
Lung ultrasound in children and adolescents with long-term effects of COVID-19: Initial results
title Lung ultrasound in children and adolescents with long-term effects of COVID-19: Initial results
title_full Lung ultrasound in children and adolescents with long-term effects of COVID-19: Initial results
title_fullStr Lung ultrasound in children and adolescents with long-term effects of COVID-19: Initial results
title_full_unstemmed Lung ultrasound in children and adolescents with long-term effects of COVID-19: Initial results
title_short Lung ultrasound in children and adolescents with long-term effects of COVID-19: Initial results
title_sort lung ultrasound in children and adolescents with long-term effects of covid-19: initial results
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080098/
https://www.ncbi.nlm.nih.gov/pubmed/37033176
http://dx.doi.org/10.3389/fped.2023.1112881
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