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Reduction of the skin‑effect dose of IMRT plan for patients with cancer in pelvic region

In the present study, it was aimed to investigate the optimized plan of radiotherapy with dose modulation in the pelvis to reduce the dose on the skin in patients having pelvic region radiotherapy. The series of images of 45 pelvic cancer patients were selected, intensity-modulated radiation therapy...

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Autores principales: Vinh, Quang Bui, Quoc, Soai Dang, Van, Toan Hoang, Vu, Truong, Thi, Tuyet Pham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080264/
https://www.ncbi.nlm.nih.gov/pubmed/37035470
http://dx.doi.org/10.3892/mco.2023.2639
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author Vinh, Quang Bui
Quoc, Soai Dang
Van, Toan Hoang
Vu, Truong
Thi, Tuyet Pham
author_facet Vinh, Quang Bui
Quoc, Soai Dang
Van, Toan Hoang
Vu, Truong
Thi, Tuyet Pham
author_sort Vinh, Quang Bui
collection PubMed
description In the present study, it was aimed to investigate the optimized plan of radiotherapy with dose modulation in the pelvis to reduce the dose on the skin in patients having pelvic region radiotherapy. The series of images of 45 pelvic cancer patients were selected, intensity-modulated radiation therapy (IMRT) plan was made, the skin dose reduction was optimized, and evaluated verifying the plan verification. As a result, skin volume receiving dose ≥10, ≥20, ≥30, ≥40 and ≥50 Gy of the IMRT Skin plan were all less than those of the IMRT plan. Particularly, skin volumes receiving doses ≥20, ≥30, ≥40 and ≥50 Gy of the Skin IMRT plan were markedly lower than those of the IMRT plan, the reduction values were 8.76, 18.83, 46.84 and 100%, respectively. Furthermore, the Skin IMRT plan was no longer affected by the 50 Gy dose. In conclusion, the present study revealed that the skin's dose can be decreased with optimal plan processing; thus, this decrease of the skin's dose ensures the continuation of radiotherapy and improved life quality of the patient.
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spelling pubmed-100802642023-04-08 Reduction of the skin‑effect dose of IMRT plan for patients with cancer in pelvic region Vinh, Quang Bui Quoc, Soai Dang Van, Toan Hoang Vu, Truong Thi, Tuyet Pham Mol Clin Oncol Articles In the present study, it was aimed to investigate the optimized plan of radiotherapy with dose modulation in the pelvis to reduce the dose on the skin in patients having pelvic region radiotherapy. The series of images of 45 pelvic cancer patients were selected, intensity-modulated radiation therapy (IMRT) plan was made, the skin dose reduction was optimized, and evaluated verifying the plan verification. As a result, skin volume receiving dose ≥10, ≥20, ≥30, ≥40 and ≥50 Gy of the IMRT Skin plan were all less than those of the IMRT plan. Particularly, skin volumes receiving doses ≥20, ≥30, ≥40 and ≥50 Gy of the Skin IMRT plan were markedly lower than those of the IMRT plan, the reduction values were 8.76, 18.83, 46.84 and 100%, respectively. Furthermore, the Skin IMRT plan was no longer affected by the 50 Gy dose. In conclusion, the present study revealed that the skin's dose can be decreased with optimal plan processing; thus, this decrease of the skin's dose ensures the continuation of radiotherapy and improved life quality of the patient. D.A. Spandidos 2023-03-30 /pmc/articles/PMC10080264/ /pubmed/37035470 http://dx.doi.org/10.3892/mco.2023.2639 Text en Copyright: © Vinh et al. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Articles
Vinh, Quang Bui
Quoc, Soai Dang
Van, Toan Hoang
Vu, Truong
Thi, Tuyet Pham
Reduction of the skin‑effect dose of IMRT plan for patients with cancer in pelvic region
title Reduction of the skin‑effect dose of IMRT plan for patients with cancer in pelvic region
title_full Reduction of the skin‑effect dose of IMRT plan for patients with cancer in pelvic region
title_fullStr Reduction of the skin‑effect dose of IMRT plan for patients with cancer in pelvic region
title_full_unstemmed Reduction of the skin‑effect dose of IMRT plan for patients with cancer in pelvic region
title_short Reduction of the skin‑effect dose of IMRT plan for patients with cancer in pelvic region
title_sort reduction of the skin‑effect dose of imrt plan for patients with cancer in pelvic region
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080264/
https://www.ncbi.nlm.nih.gov/pubmed/37035470
http://dx.doi.org/10.3892/mco.2023.2639
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