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Reduction of the skin‑effect dose of IMRT plan for patients with cancer in pelvic region
In the present study, it was aimed to investigate the optimized plan of radiotherapy with dose modulation in the pelvis to reduce the dose on the skin in patients having pelvic region radiotherapy. The series of images of 45 pelvic cancer patients were selected, intensity-modulated radiation therapy...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080264/ https://www.ncbi.nlm.nih.gov/pubmed/37035470 http://dx.doi.org/10.3892/mco.2023.2639 |
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author | Vinh, Quang Bui Quoc, Soai Dang Van, Toan Hoang Vu, Truong Thi, Tuyet Pham |
author_facet | Vinh, Quang Bui Quoc, Soai Dang Van, Toan Hoang Vu, Truong Thi, Tuyet Pham |
author_sort | Vinh, Quang Bui |
collection | PubMed |
description | In the present study, it was aimed to investigate the optimized plan of radiotherapy with dose modulation in the pelvis to reduce the dose on the skin in patients having pelvic region radiotherapy. The series of images of 45 pelvic cancer patients were selected, intensity-modulated radiation therapy (IMRT) plan was made, the skin dose reduction was optimized, and evaluated verifying the plan verification. As a result, skin volume receiving dose ≥10, ≥20, ≥30, ≥40 and ≥50 Gy of the IMRT Skin plan were all less than those of the IMRT plan. Particularly, skin volumes receiving doses ≥20, ≥30, ≥40 and ≥50 Gy of the Skin IMRT plan were markedly lower than those of the IMRT plan, the reduction values were 8.76, 18.83, 46.84 and 100%, respectively. Furthermore, the Skin IMRT plan was no longer affected by the 50 Gy dose. In conclusion, the present study revealed that the skin's dose can be decreased with optimal plan processing; thus, this decrease of the skin's dose ensures the continuation of radiotherapy and improved life quality of the patient. |
format | Online Article Text |
id | pubmed-10080264 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-100802642023-04-08 Reduction of the skin‑effect dose of IMRT plan for patients with cancer in pelvic region Vinh, Quang Bui Quoc, Soai Dang Van, Toan Hoang Vu, Truong Thi, Tuyet Pham Mol Clin Oncol Articles In the present study, it was aimed to investigate the optimized plan of radiotherapy with dose modulation in the pelvis to reduce the dose on the skin in patients having pelvic region radiotherapy. The series of images of 45 pelvic cancer patients were selected, intensity-modulated radiation therapy (IMRT) plan was made, the skin dose reduction was optimized, and evaluated verifying the plan verification. As a result, skin volume receiving dose ≥10, ≥20, ≥30, ≥40 and ≥50 Gy of the IMRT Skin plan were all less than those of the IMRT plan. Particularly, skin volumes receiving doses ≥20, ≥30, ≥40 and ≥50 Gy of the Skin IMRT plan were markedly lower than those of the IMRT plan, the reduction values were 8.76, 18.83, 46.84 and 100%, respectively. Furthermore, the Skin IMRT plan was no longer affected by the 50 Gy dose. In conclusion, the present study revealed that the skin's dose can be decreased with optimal plan processing; thus, this decrease of the skin's dose ensures the continuation of radiotherapy and improved life quality of the patient. D.A. Spandidos 2023-03-30 /pmc/articles/PMC10080264/ /pubmed/37035470 http://dx.doi.org/10.3892/mco.2023.2639 Text en Copyright: © Vinh et al. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
spellingShingle | Articles Vinh, Quang Bui Quoc, Soai Dang Van, Toan Hoang Vu, Truong Thi, Tuyet Pham Reduction of the skin‑effect dose of IMRT plan for patients with cancer in pelvic region |
title | Reduction of the skin‑effect dose of IMRT plan for patients with cancer in pelvic region |
title_full | Reduction of the skin‑effect dose of IMRT plan for patients with cancer in pelvic region |
title_fullStr | Reduction of the skin‑effect dose of IMRT plan for patients with cancer in pelvic region |
title_full_unstemmed | Reduction of the skin‑effect dose of IMRT plan for patients with cancer in pelvic region |
title_short | Reduction of the skin‑effect dose of IMRT plan for patients with cancer in pelvic region |
title_sort | reduction of the skin‑effect dose of imrt plan for patients with cancer in pelvic region |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080264/ https://www.ncbi.nlm.nih.gov/pubmed/37035470 http://dx.doi.org/10.3892/mco.2023.2639 |
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