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Pharmacological reversal of post-transcriptional alterations implicated in alcohol-induced alveolar macrophage dysfunction

Alcohol use disorders (AUD) cause alveolar macrophage (AM) immune dysfunction and increase risk of lung infections. Excessive alcohol use causes AM oxidative stress, which impairs AM phagocytosis and pathogen clearance from the alveolar space. Alcohol induces expression of NADPH oxidases (Noxes), pr...

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Detalles Bibliográficos
Autores principales:	Yeligar, Samantha M., Harris, Frank L., Brown, Lou Ann S., Hart, C. Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080543/ https://www.ncbi.nlm.nih.gov/pubmed/36328183 http://dx.doi.org/10.1016/j.alcohol.2022.10.003

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